Interaksi Rasagilin

Rasagilin (Azilect), golongan penghambat MAO, memiliki 224 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 117 mayor, 98 moderat, 9 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (117)

  • Amfetaminstimulan SSPMayor

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [ see Warnings and Precautions (5.7) , Drug Interactions (7.1) ]. (label Amfetamin, Kontraindikasi)

  • Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6.2 )] . taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive… (label Amfetamin dan dekstroamfetamin, Kontraindikasi)

  • Amitriptilinantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Amoksapinantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Apraklonidinagonis alfa-adrenergikMayor

    CONTRAINDICATIONS IOPIDINE 1% Ophthalmic Solution is contraindicated for patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine. (label Apraklonidin, Kontraindikasi)

  • Atomoksetinpenghambat ambilan kembali norepinefrinMayor

    Taking, or within 14 days of stopping, a monoamine oxidase inhibitor (MAOI) [see Drug Interactions (7) ] . (label Atomoksetin, Kontraindikasi)

  • …Precautions (5.2) ] • Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [ see Warnings and Precautions (5.5) ] • Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [ see Warnings and Precautions (5.7), Drug Interactions (7) ] • Known or suspected gastrointestinal obstruction,… (label Beladona dan opium, Kontraindikasi)

  • Benzfetaminstimulan SSPMayor

    Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. (label Benzfetamin, Kontraindikasi)

  • Rasagiline is contraindicated for use with dextromethorphan because of risk of episode of psychosis or bizarre behavior. (label Rasagilin, Kontraindikasi)

  • BuprenorfinopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions (5.2) ]. (label Buprenorfin, Interaksi obat)

  • Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma). (label Buprenorfin dan nalokson, Interaksi obat)

  • BupropionantidepresanMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Buspironobat serotonergikMayor

    The use of monoamine oxidase inhibitors (MAOIs) intended to treat depression with buspirone or within 14 days of stopping treatment with buspirone is contraindicated because of an increased risk of serotonin syndrome and/or elevated blood pressure. (label Buspiron, Kontraindikasi)

  • …respiratory depression [see Warnings and Precautions ( 5.9 ) ] Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment[see Warnings and Precautions ( 5.9 ) ] Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Warnings and Precautions ( 5.10 ) / Drug Interactions ( 7 ) ]. (label Butalbital, aspirin, kafein, dan kodein, Kontraindikasi)

  • …Precautions ( 5.2 )] • Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see Warnings and Precautions ( 5.10 )] • Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Warnings and Precautions ( 5.11 ), Drug Interactions ( 7 )] • Known or suspected gastrointestinal obstruction,… (label Butalbital, parasetamol, kafein, dan kodein, Kontraindikasi)

  • ButorfanolopioidMayor

    …medical attention if they ‎experience symptoms of hyperalgesia, including worsening pain, increased ‎sensitivity to pain, or new pain [see WARNINGS ; ADVERSE REACTIONS ].‎ Serotonin Syndrome Inform patients that butorphanol tartrate could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (label Butorfanol, Perhatian)

  • DeksklorfeniraminantihistaminMayor

    Antihistamines are also contraindicated in the following conditions: Hypersensitivity to dexchlorpheniramine maleate or other antihistamines of similar chemical structure Monoamine oxidase inhibitor therapy (See Drug Interaction section) (label Deksklorfeniramin, Kontraindikasi)

  • Deksmetilfenidatstimulan SSPMayor

    • Concomitant treatment with monoamine oxidase inhibitors (MAOIs) or within 14 days following discontinuation of treatment with an MAOI, because of the risk of hypertensive crises [see Drug Interactions ( 7.1 )] . (label Deksmetilfenidat, Kontraindikasi)

  • Dekstroamfetaminstimulan SSPMayor

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Drug Interactions ]. (label Dekstroamfetamin, Kontraindikasi)

  • Dekstrometorfanobat serotonergikMayor

    Rasagiline is contraindicated for use with dextromethorphan because of risk of episode of psychosis or bizarre behavior. (label Rasagilin, Kontraindikasi)

  • Dekstrometorfan dan kuinidinobat serotonergikMayor

    Rasagiline is contraindicated for use with dextromethorphan because of risk of episode of psychosis or bizarre behavior. (label Rasagilin, Kontraindikasi)

  • Desipraminantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Deutetrabenazinpenghambat VMAT2Mayor

    Taking monoamine oxidase inhibitors (MAOIs). (label Deutetrabenazin, Kontraindikasi)

  • Dietilpropionstimulan SSPMayor

    During or within 14 days following the administration of monoamine oxidase inhibitors, hypertensive crises may result. (label Dietilpropion, Kontraindikasi)

  • Avoid use of diphenoxylate hydrochloride and atropine sulfate in patients who take MAOIs and monitor for signs and symptoms of hypertensive crisis (headache, hyperthermia, hypertension). (label Difenoksilat dan atropin, Interaksi obat)

  • Doksepinantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Doksilamin dan piridoksinantihistaminMayor

    …Known hypersensitivity to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredient in the formulation Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of doxylamine succinate and pyridoxine hydrochloride delayed-release tablets [ see Drug Interactions… (label Doksilamin dan piridoksin, Kontraindikasi)

  • DroksidopasimpatomimetikMayor

    However, based on mechanism of action, the use of non-selective MAO inhibitors and linezolid should be avoided as there is a potential for increased blood pressure when taken with NORTHERA. (label Droksidopa, Interaksi obat)

  • DuloksetinSNRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • EletriptantriptanMayor

    Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs and MAO inhibitors [see Warnings and Precautions (5.7) ]. (label Eletriptan, Interaksi obat)

  • EsitalopramSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Fendimetrazinstimulan SSPMayor

    …coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension, pulmonary hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy (see PRECAUTIONS, Pregnancy ) • Nursing • Use in combination with other… (label Fendimetrazin, Kontraindikasi)

  • Fenelzinpenghambat MAOMayor

    John’s wort, cyclobenzaprine, or another (selective or non-selective) MAO inhibitor ( 4 ) (label Rasagilin, Kontraindikasi)

  • FentanilopioidMayor

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (label Fentanil, Peringatan dan perhatian)

  • Fenterminstimulan SSPMayor

    …cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) • During or within 14 days following the administration of monoamine oxidase inhibitors • Hyperthyroidism • Glaucoma • Agitated states • History of drug abuse • Pregnancy [ see Use in Specific Populations () ] • Nursing [ see Use in Specific… (label Fentermin, Kontraindikasi)

  • Fentermin dan topiramatstimulan SSPMayor

    …Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ] With glaucoma [see Warnings and Precautions (5.3) ] With hyperthyroidism Taking or within 14 days of stopping a monoamine oxidase inhibitors [see Drug Interactions (7) ] With known hypersensitivity to phentermine, topiramate or any of the excipients in phentermine and topiramate extended-release… (label Fentermin dan topiramat, Kontraindikasi)

  • FluoksetinSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • FluvoksaminSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • FrovatriptantriptanMayor

    Selective Serotonin Reuptake Inhibitors / Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during combined use of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [ see Warnings and Precautions (5.7) ]. (label Frovatriptan, Interaksi obat)

  • Granisetronobat yang memperpanjang interval QTMayor

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of granisetron and other serotonergic drugs. (label Granisetron, Peringatan dan perhatian)

  • HidrokodonopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions (5.3) ] . (label Hidrokodon, Interaksi obat)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (label Hidrokodon dan homatropin, Interaksi obat)

  • Monoamine Oxidase Inhibitors (MAOIs) MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma). (label Hidrokodon dan ibuprofen, Interaksi obat)

  • Serotonergic drugs : Concomitant use may result in serotonin syndrome. (label Hidrokodon dan klorfeniramin, Interaksi obat)

  • The use of hydrocodone bitartrate and acetaminophen tablets is not recommended for patients taking MAOIs or within 14 days of stopping such treatment. (label Hidrokodon dan parasetamol, Interaksi obat)

  • HidromorfonopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions ( 5.3 )]. (label Hidromorfon, Interaksi obat)

  • Imipraminantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • IsoniazidantibiotikMayor

    John’s wort, cyclobenzaprine, or another (selective or non-selective) MAO inhibitor ( 4 ) (label Rasagilin, Kontraindikasi)

  • KarbamazepinantikonvulsanMayor

    Concomitant use of monoamine oxidase inhibitors (MAOIs). (label Karbamazepin, Kontraindikasi)

  • Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with levodopa or carbidopa-levodopa combination products with or without carbidopa. (label Karbidopa, Kontraindikasi)

  • Karbidopa dan levodopaobat dopaminergikMayor

    DUOPA is contraindicated in patients who are currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or have recently (within 2 weeks) taken a nonselective MAO inhibitor. (label Karbidopa dan levodopa, Kontraindikasi)

  • Carbidopa, levodopa and entacapone tablets is contraindicated in patients: Taking nonselective monoamine oxidase (MAO) inhibitors (e.g., phenelzine and tranylcypromine). (label Karbidopa, levodopa, dan entakapon, Kontraindikasi)

  • KarbinoksaminantihistaminMayor

    …because deaths have been reported in this age group [see Warnings and Precautions (5.1)]. patients who are hypersensitive to carbinoxamine maleate or any of the inactive ingredients in Carbinoxamine Maleate Extended-Release Oral Suspension [see Warnings and Precautions (5.4)]. patients who are taking monoamine oxidase inhibitors (MAOI) [see Drug Interactions (7)]. (label Karbinoksamin, Kontraindikasi)

  • Klomipraminantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • KodeinopioidMayor

    • Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Warnings and Precautions ( 5.10 ), Drug Interactions ( 7 )]. (label Kodein, Kontraindikasi)

  • Levodopaobat dopaminergikMayor

    INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor. (label Levodopa, Kontraindikasi)

  • May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • LevorfanolopioidMayor

    Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (label Levorfanol, Perhatian)

  • LinezolidantibiotikMayor

    John’s wort, cyclobenzaprine, or another (selective or non-selective) MAO inhibitor ( 4 ) (label Rasagilin, Kontraindikasi)

  • Lisdeksamfetaminstimulan SSPMayor

    Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1) ] . (label Lisdeksamfetamin, Kontraindikasi)

  • Litiumobat serotonergikMayor

    If concomitant use of lithium with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms. (label Litium, Peringatan dan perhatian)

  • MetadonopioidMayor

    Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome [see Warnings and Precautions ( 5.2 )] . (label Rasagilin, Kontraindikasi)

  • Metaksalonpelemas ototMayor

    Serotonin syndrome has resulted from concomitant use of metaxalone (within the recommended dosage range) and other serotonergic drugs [see Warnings and Precautions (5.1) ]. (label Metaksalon, Interaksi obat)

  • Metamfetaminstimulan SSPMayor

    Hypersensitivity reactions such as angioedema and anaphylactic reactions have been reported in patients treated with other amphetamine products [see Adverse Reactions ( 6 )]. taking monoamine oxidase inhibitors (MAOIs), or within 14 days following discontinuation of treatment with an MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because… (label Metamfetamin, Kontraindikasi)

  • MetildopaantihipertensiMayor

    CONTRAINDICATIONS Methyldopa is contraindicated in patients: – with active hepatic disease, such as acute hepatitis and active cirrhosis. – with liver disorders previously associated with methyldopa therapy (see WARNINGS ). – with hypersensitivity to any component of this product. – on therapy with monoamine oxidase (MAO) inhibitors. (label Metildopa, Kontraindikasi)

  • Metilen birupenghambat MAOMayor

    John’s wort, cyclobenzaprine, or another (selective or non-selective) MAO inhibitor ( 4 ) (label Rasagilin, Kontraindikasi)

  • Metilfenidatstimulan SSPMayor

    Concomitant treatment with monoamine oxidase inhibitors (MAOIs), and also within a minimum of 14 days following discontinuation of treatment with a monoamine oxidase inhibitor because of the risk of hypertensive crisis [see Drug Interactions (7.1) ]. (label Metilfenidat, Kontraindikasi)

  • Metoklopramidantagonis dopaminMayor

    In one study in hypertensive patients, intravenously administered metoclopramide was shown to release catecholamines; hence, avoid use in patients with hypertension or in patients taking monoamine oxidase inhibitors [see Drug Interactions ( 7.1 )] . (label Metoklopramid, Peringatan dan perhatian)

  • Midodrinagonis alfa-adrenergikMayor

    Avoid use of MAO inhibitors or linezolid with midodrine. (label Midodrin, Interaksi obat)

  • MilnasipranSNRIMayor

    Concomitant use of rasagiline with one of many classes of antidepressants (e.g., SSRIs, SNRIs, triazolopyridine, tricyclic or tetracyclic antidepressants) is not recommended [see Drug Interactions ( 7.5 )]. (label Rasagilin, Peringatan dan perhatian)

  • MirtazapinantidepresanMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • MorfinopioidMayor

    • Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Warnings and Precautions ( 5.9 ) and Drug Interactions ( 7 )]. (label Morfin, Kontraindikasi)

  • NalbufinopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) MAOI (e.g., phenelzine, tranylcypromine, linezolid) interactions with opioids may manifest as serotonin syndrome [see PRECAUTIONS; Drug Interactions ] or opioid toxicity (e.g., respiratory depression, coma [see WARNINGS ]). (label Nalbufin, Interaksi obat)

  • Naltrekson dan bupropionantagonis opioidMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • NaratriptantriptanMayor

    Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during co-administration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (label Naratriptan, Interaksi obat)

  • NefazodonantidepresanMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Nortriptilinantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • OksikodonopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions (5.3) ] . (label Oksikodon, Interaksi obat)

  • Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions ( 5.2)]. (label Oksikodon dan parasetamol, Interaksi obat)

  • OksimorfonopioidMayor

    Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact: MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma) [see Warnings and Precautions (5.2) ]. (label Oksimorfon, Interaksi obat)

  • Olanzapin dan fluoksetinantipsikotikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • OliseridinopioidMayor

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (label Oliseridin, Interaksi obat)

  • Ondansetronobat yang memperpanjang interval QTMayor

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of Ondansetron Injection and other serotonergic drugs. (label Ondansetron, Peringatan dan perhatian)

  • Palonosetronobat serotonergikMayor

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of POSFREA and other serotonergic drugs. (label Palonosetron, Peringatan dan perhatian)

  • …respiratory depression ( see WARNINGS ). acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment ( see WARNINGS ). concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days ( see WARNINGS ). known or suspected gastrointestinal obstruction, including paralytic ileus ( see WARNINGS… (label Parasetamol dan kodein, Kontraindikasi)

  • ParoksetinSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (label Pentazosin dan nalokson, Perhatian)

  • PetidinopioidMayor

    Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome [see Warnings and Precautions ( 5.2 )] . (label Rasagilin, Kontraindikasi)

  • Rasagiline is contraindicated for use with dextromethorphan because of risk of episode of psychosis or bizarre behavior. (label Rasagilin, Kontraindikasi)

  • Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within 14 days [ see Warnings and Precautions (5.16) , Drug Interactions (7.6) ]. (label Prometazin dan kodein, Kontraindikasi)

  • Protriptilinantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • PseudoefedrindekongestanMayor

    Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. (label Pseudoefedrin, Peringatan)

  • RemifentanilopioidMayor

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (label Remifentanil, Peringatan dan perhatian)

  • RizatriptantriptanMayor

    Monoamine Oxidase Inhibitors MAXALT is contraindicated in patients taking MAO-A inhibitors and non-selective MAO inhibitors. (label Rizatriptan, Interaksi obat)

  • Selegilinpenghambat MAOMayor

    …concomitant use of an antidepressant (e.g., selective serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a nonselective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (Eldepryl) and rasagiline . (label Rasagilin, Peringatan dan perhatian)

  • SertralinSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Siklobenzaprinpelemas ototMayor

    John’s wort and with cyclobenzaprine. (label Rasagilin, Kontraindikasi)

  • SiproheptadinantihistaminMayor

    Monoamine oxidase inhibitor therapy (See DRUG INTERACTIONS ). (label Siproheptadin, Kontraindikasi)

  • SitalopramSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Solriamfetolstimulan SSPMayor

    Concomitant use of rasagiline with one of many classes of antidepressants (e.g., SSRIs, SNRIs, triazolopyridine, tricyclic or tetracyclic antidepressants) is not recommended [see Drug Interactions ( 7.5 )]. (label Rasagilin, Peringatan dan perhatian)

  • St. John's wortHerbal dan suplemenMayor

    Mengombinasikan St. John's wort dengan antidepresan dan obat serotonergik lain meningkatkan risiko sindrom serotonin. (NCCIH, St. John's Wort)

  • SumatriptantriptanMayor

    Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)] . (label Sumatriptan, Interaksi obat)

  • Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome Clinical Impact: Cases of serotonin syndrome have been reported during coadministration of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.11)] . (label Sumatriptan dan naproksen, Interaksi obat)

  • TapentadolopioidMayor

    …suspected paralytic ileus [see Warnings and Precautions (5.12) ] Hypersensitivity to tapentadol (e.g., anaphylaxis, angioedema) or to any other ingredients of the product [see Adverse Reactions (6.2) ] Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Drug Interactions (7) ] Significant respiratory depression ( 4 ) (label Tapentadol, Kontraindikasi)

  • Tetrabenazinpenghambat VMAT2Mayor

    • Taking monoamine oxidase inhibitors (MAOIs). (label Tetrabenazin, Kontraindikasi)

  • TramadolopioidMayor

    Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome [see Warnings and Precautions ( 5.2 )] . (label Rasagilin, Kontraindikasi)

  • Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome [see Warnings and Precautions ( 5.2 )] . (label Rasagilin, Kontraindikasi)

  • Tranilsiprominpenghambat MAOMayor

    …concomitant use of an antidepressant (e.g., selective serotonin reuptake inhibitors-SSRIs, serotonin-norepinephrine reuptake inhibitors-SNRIs, tricyclic antidepressants, tetracyclic antidepressants, triazolopyridine antidepressants) and a nonselective MAOI (e.g., phenelzine, tranylcypromine) or selective MAO-B inhibitors, such as selegiline (Eldepryl) and rasagiline . (label Rasagilin, Peringatan dan perhatian)

  • TrazodonantidepresanMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Trimipraminantidepresan trisiklikMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Valbenazinpenghambat VMAT2Mayor

    Dose adjustments due to drug interactions ( 2.4 , 7.1 ): Factors Dose Adjustments for INGREZZA and INGREZZA SPRINKLE Use of MAOIs with INGREZZA or INGREZZA SPRINKLE Avoid concomitant use with MAOIs. (label Valbenazin, Interaksi obat)

  • VenlafaksinSNRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • VilazodonSSRIMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • Viloksazinpenghambat ambilan kembali norepinefrinMayor

    Qelbree is contraindicated in patients: receiving concomitant treatment with monoamine oxidase inhibitors (MAOI), or within 14 days following discontinuing an MAOI, because of an increased risk of hypertensive crisis [see Drug Interactions (7.1) ] . receiving concomitant administration of sensitive CYP1A2 substrates or CYP1A2 substrates with a narrow therapeutic… (label Viloksazin, Kontraindikasi)

  • VortioksetinantidepresanMayor

    May cause serotonin syndrome when used with antidepressants ( 5.2 ) (label Rasagilin, Peringatan dan perhatian)

  • ZiprasidonantipsikotikMayor

    • Concomitant use of monoamine oxidase inhibitors (MAOIs), or use within 14 days of stopping MAOIs. (label Ziprasidon, Kontraindikasi)

Interaksi moderat (98)

  • AmantadinantikolinergikModerat

    Decreasing the levodopa dose may lessen or eliminate this side effect ( 5.7 ) (label Rasagilin, Peringatan dan perhatian)

  • Arformoterolagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • AripiprazolantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Armodafinilstimulan SSPModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Artikain dan epinefrinanestetik lokalModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • AsenapinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • BrekspiprazolantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Brimonidinagonis alfa-adrenergikModerat

    Monoamine oxidase inhibitors may result in increased hypotension. (label Brimonidin, Interaksi obat)

  • Brimonidin dan timololagonis alfa-adrenergikModerat

    Monoamine oxidase inhibitors may result in increased hypotension. (label Brimonidin dan timolol, Interaksi obat)

  • Bromokriptinagonis dopaminModerat

    For this reason, prescribers should monitor patients for drowsiness or sleepiness, because some of the events occur well after initiation of treatment with dopaminergic medication. (label Rasagilin, Peringatan dan perhatian)

  • Budesonid dan formoterolkortikosteroidModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Bupivakainanestetik lokalModerat

    …of Adverse Reactions Due to Drug Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors… (label Bupivakain, Peringatan dan perhatian)

  • Bupivakain dan epinefrinanestetik lokalModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Drug Interactions The CNS effects of butalbital may be enhanced by monoamine oxidase (MAO) inhibitors. (label Butalbital dan parasetamol, Interaksi obat)

  • Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Deferasirokssuplemen zat besiModerat

    Ciprofloxacin or Other CYP1A2 Inhibitors Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. (label Rasagilin, Peringatan dan perhatian)

  • DiazepambenzodiazepinModerat

    …be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (label Diazepam, Interaksi obat)

  • DifenhidraminantihistaminModerat

    MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines. (label Difenhidramin, Interaksi obat)

  • DisikloverinantikolinergikModerat

    …drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (label Disikloverin, Interaksi obat)

  • DobutaminsimpatomimetikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Droperidolantagonis dopaminModerat

    …1) clinically significant bradycardia (less than 50 bpm), 2) any clinically significant cardiac disease, 3) treatment with Class I and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval (see PRECAUTIONS, Drug Interactions ), and 6) electrolyte imbalance,… (label Droperidol, Peringatan)

  • EfedrinsimpatomimetikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • EpinefrinsimpatomimetikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Ergotamin dan kafeinalkaloid ergotModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • EstazolambenzodiazepinModerat

    The action of the benzodiazepines may be potentiated by anticonvulsants, antihistamines, alcohol, barbiturates, monoamine oxidase inhibitors, narcotics, phenothiazines, psychotropic medications, or other drugs that produce CNS depression. (label Estazolam, Interaksi obat)

  • FenilefrindekongestanModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • FlufenazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Flutikason dan salmeterolkortikosteroidModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Formoterolagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • GlibenklamidsulfonilureaModerat

    …Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (label Glibenklamid, Interaksi obat)

  • GlimepiridsulfonilureaModerat

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (label Glimepirid, Interaksi obat)

  • GlipizidsulfonilureaModerat

    …increase the susceptibility to and/or intensity of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory… (label Glipizid, Interaksi obat)

  • Glipizid dan metforminsulfonilureaModerat

    Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (label Glipizid dan metformin, Perhatian)

  • HaloperidolantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • HidralazinvasodilatorModerat

    Drug Interactions MAO inhibitors should be used with caution in patients receiving hydralazine. (label Hidralazin, Interaksi obat)

  • IloperidonantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Insulin aspartinsulinModerat

    Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (label Insulin aspart, Interaksi obat)

  • Insulin degludekinsulinModerat

    …Degludec Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (label Insulin degludek, Interaksi obat)

  • Insulin detemirinsulinModerat

    …with LEVEMIR Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (label Insulin detemir, Interaksi obat)

  • Insulin glargininsulinModerat

    …Glargine-yfgn Drugs that May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors,… (label Insulin glargin, Interaksi obat)

  • Insulin lisproinsulinModerat

    Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (label Insulin lispro, Interaksi obat)

  • …Significant Drug Interactions with AFREZZA Antidiabetic agents, Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose… (label Insulin reguler (manusia), Interaksi obat)

  • Ipratropium dan salbutamolantikolinergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Isoflurananestetik umumModerat

    Concomitant Use with MAO Inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (label Isofluran, Interaksi obat)

  • Isoprenalinagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Kabergolinagonis dopaminModerat

    For this reason, prescribers should monitor patients for drowsiness or sleepiness, because some of the events occur well after initiation of treatment with dopaminergic medication. (label Rasagilin, Peringatan dan perhatian)

  • Kanabidiol (obat resep)antikonvulsanModerat

    Ciprofloxacin or Other CYP1A2 Inhibitors Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. (label Rasagilin, Peringatan dan perhatian)

  • KariprazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Karvedilolpenyekat betaModerat

    Hypotensive agents (e.g., reserpine, MAO inhibitors, clonidine) may increase the risk of hypotension and/or severe bradycardia. (label Karvedilol, Interaksi obat)

  • KlemastinantihistaminModerat

    Monoamine oxidase (MAO) inhibitors prolong and intensify the anticholinergic effects of antihistamines. (label Klemastin, Interaksi obat)

  • KlonazepambenzodiazepinModerat

    …Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (label Klonazepam, Interaksi obat)

  • KlorazepatbenzodiazepinModerat

    The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (label Klorazepat, Interaksi obat)

  • Kloroprokainanestetik lokalModerat

    Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (label Kloroprokain, Perhatian)

  • KlorpromazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • KlozapinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Kokainanestetik lokalModerat

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (label Kokain, Interaksi obat)

  • KuetiapinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Levosalbutamolagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Lidokainanestetik lokalModerat

    Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (label Lidokain, Interaksi obat)

  • Lidokain dan epinefrinanestetik lokalModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • LoksapinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • LumateperonantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • LurasidonantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • MeksiletinantiaritmiaModerat

    Ciprofloxacin or Other CYP1A2 Inhibitors Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. (label Rasagilin, Peringatan dan perhatian)

  • Mepivakainanestetik lokalModerat

    Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (label Mepivakain, Peringatan)

  • Metoprololpenyekat betaModerat

    Catecholamine depleting drugs (e.g., reserpine, monoamine oxidase (MAO) inhibitors) may have an additive effect when given with beta-blocking agents. (label Metoprolol, Interaksi obat)

  • Catecholamine-depleting drugs (e.g., MAO inhibitors): Hypotension, bradycardia. (label Metoprolol dan hidroklorotiazid, Interaksi obat)

  • Mirabegronagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Modafinilstimulan SSPModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • NateglinidmeglitinidModerat

    …Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan, thioctic acid,… (label Nateglinid, Interaksi obat)

  • OksimetazolindekongestanModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • OlanzapinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • PaliperidonantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • PerfenazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • PimavanserinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • PimozidantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Pioglitazon dan glimepiridtiazolidindionModerat

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (label Pioglitazon dan glimepirid, Interaksi obat)

  • Pramipeksolagonis dopaminModerat

    For this reason, prescribers should monitor patients for drowsiness or sleepiness, because some of the events occur well after initiation of treatment with dopaminergic medication. (label Rasagilin, Peringatan dan perhatian)

  • Prilokain dan epinefrinanestetik lokalModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • ProklorperazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • PrometazinantihistaminModerat

    Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. (label Prometazin, Interaksi obat)

  • RisperidonantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Ropinirolagonis dopaminModerat

    For this reason, prescribers should monitor patients for drowsiness or sleepiness, because some of the events occur well after initiation of treatment with dopaminergic medication. (label Rasagilin, Peringatan dan perhatian)

  • Salbutamolagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Salmeterolagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Sevoflurananestetik umumModerat

    Non-selective MAO-inhibitors Concomitant use of MAO inhibitors and inhalational anesthetics may increase the risk of hemodynamic instability during surgery or medical procedures. (label Sevofluran, Interaksi obat)

  • Simetidinpenghambat H2Moderat

    Ciprofloxacin or Other CYP1A2 Inhibitors Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. (label Rasagilin, Peringatan dan perhatian)

  • SiprofloksasinfluorokuinolonModerat

    …with rasagiline, patients should be advised of the potential to develop drowsiness and specifically asked about factors that may increase the risk with rasagiline such as concomitant sedating medications, the presence of sleep disorders, and concomitant medications that increase rasagiline plasma levels (e.g., ciprofloxacin) [see Drug Interactions ( 7.6 )] . (label Rasagilin, Peringatan dan perhatian)

  • Suksinilkolinpenyekat neuromuskularModerat

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (label Suksinilkolin, Interaksi obat)

  • Terbutalinagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • TioridazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • TiotiksenantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • TrifluoperazinantipsikotikModerat

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (label Rasagilin, Peringatan dan perhatian)

  • Umeklidinium dan vilanterolantikolinergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Vibegronagonis beta-adrenergikModerat

    Hypertensive crisis has been reported in patients taking the recommended dose of rasagiline and sympathomimetic medications. (label Rasagilin, Interaksi obat)

  • Zileutonpenghambat CYP1A2Moderat

    Ciprofloxacin or Other CYP1A2 Inhibitors Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. (label Rasagilin, Peringatan dan perhatian)

Penyebutan minor (9)

  • Drug Interactions Since the chemical structure of difenoxin hydrochloride is similar to meperidine hydrochloride, the concurrent use of MOTOFEN ® with monoamine oxidase inhibitors may, in theory, precipitate a hypertensive crisis. (label Difenoksin dan atropin, Interaksi obat)

  • It is theoretically possible, therefore, that the combination of Entacapone Tablets and a non-selective MAO inhibitor (e.g., phenelzine and tranylcypromine) would result in inhibition of the majority of the pathways responsible for normal catecholamine metabolism. (label Entakapon, Peringatan)

  • Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (label Glibenklamid dan metformin, Interaksi obat)

  • Propranololpenyekat betaMinor

    Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (label Propranolol, Interaksi obat)

  • RepaglinidmeglitinidMinor

    Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (label Repaglinid, Interaksi obat)

  • TerbinafinantijamurMinor

    Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (label Terbinafin, Interaksi obat)

  • It is theoretically possible, therefore, that the combination of Tolcapone tablets and a non-selective MAO inhibitor (e.g., phenelzine and tranylcypromine) would result in inhibition of the majority of the pathways responsible for normal catecholamine metabolism. (label Tolkapon, Peringatan)

  • TriheksifenidilantikolinergikMinor

    Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (label Triheksifenidil, Interaksi obat)

  • ZolmitriptantriptanMinor

    Serotonin Syndrome Serotonin syndrome may occur with triptans, including zolmitriptan, particularly during co-administration with selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and MAO inhibitors [see Drug Interactions ( 7.5 )] . (label Zolmitriptan, Peringatan dan perhatian)

Periksa Rasagilin terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.