Interaction Checker

Interaksi Vinkristin

Vinkristin (Vincasar PFS) memiliki 97 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 51 mayor, 31 moderat, 15 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (51)

  • Abrositinibpenghambat JAKMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • AmiodaronantiaritmiaMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Aprepitantpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • AtazanavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • DarunavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Darunavir dan kobisistatantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Diltiazempenghambat kanal kalsiumMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • DronedaronantiaritmiaMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • EfavirenzantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Efavirenz, lamivudin, dan tenofovirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Elvitegravir, kobisistat, emtrisitabin, dan tenofovirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Eritromisinantibiotik makrolidaMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • EtravirinantiretroviralMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • EverolimusimunosupresanMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Flibanserindepresan SSPMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Flukonazolantijamur azolMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • FosamprenavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Fosaprepitantpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • HialuronidaseMayor

    Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis. (label Vinkristin, Peringatan kotak hitam)

  • Imatinibpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • IsoniazidantibiotikMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Itrakonazolantijamur azolMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Ivakaftorpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Ketokonazolantijamur azolMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Klaritromisinantibiotik makrolidaMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • KuinidinantiaritmiaMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Lapatinibpenghambat P-glikoproteinMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Ledipasvir dan sofosbuvirantivirusMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • LenakapavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Lopinavir dan ritonavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Mifepristonpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Mirabegronagonis beta-adrenergikMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Mitapivatpenginduksi CYP3A4Mayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • NefazodonantidepresanMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Nilotinibobat yang memperpanjang interval QTMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Nirmatrelvir dan ritonavirantivirusMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Palbosiklibpenghambat CYP3A4Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • PerampanelantikonvulsanMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Posakonazolantijamur azolMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • PropafenonantiaritmiaMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Ranolazinobat yang memperpanjang interval QTMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • RitonavirantiretroviralMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • SenobamatantikonvulsanMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • SiklosporinimunosupresanMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Simetidinpenghambat H2Mayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Sofosbuvir dan velpatasvirantivirusMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

  • Suvoreksantsedatif-hipnotikMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • TikagrelorantiplateletMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Verapamilpenghambat kanal kalsiumMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • Vorikonazolantijamur azolMayor

    Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided. (label Vinkristin, Interaksi obat)

  • ZonisamidantikonvulsanMayor

    Therefore, the concomitant use of P-gp inhibitors or inducers should be avoided. (label Vinkristin, Interaksi obat)

Interaksi moderat (31)

  • Asam valproatantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • BrivarasetamantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • Divalproeks (valproat)antikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • DoksorubisinModerat

    …treated with 6-mercaptopurine (500 mg/m 2 intravenously daily for 5 days per cycle every 2–3 weeks) and doxorubicin hydrochloride (50 mg/m 2 intravenous once per cycle every 2–3 weeks) alone or with vincristine and prednisone, all developed hepatic dysfunction manifested by increased total serum bilirubin, alkaline phosphatase and aspartate aminotransferase. (label Doksorubisin, Interaksi obat)

  • EslikarbazepinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • EtosuksimidantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • FelbamatantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • FenitoinantikonvulsanModerat

    The interaction may result from reduced absorption of phenytoin and an increase in the rate of its metabolism and elimination. (label Vinkristin, Interaksi obat)

  • FenobarbitalbarbituratModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • Fentermin dan topiramatstimulan SSPModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • FosfenitoinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • GabapentinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • GansiklovirantivirusModerat

    …drugs associated with myelosuppression or nephrotoxicity (e.g., dapsone, doxorubicin, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/ sulfamethoxazole, vinblastine, vincristine and zidovudine) Unknown Because of potential for higher toxicity, coadministration with Ganciclovir should be considered only if the potential benefits are judged to outweigh… (label Gansiklovir, Interaksi obat)

  • Kanabidiol (obat resep)antikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • KarbamazepinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • KlobazambenzodiazepinModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • KlonazepambenzodiazepinModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • LakosamidantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • LamotriginantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • LevetirasetamantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • MetsuksimidantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • OkskarbazepinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • PregabalinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • PrimidonantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • RufinamidantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • SitarabinantimetabolitModerat

    Drug Interactions Reversible decreases in steady-state plasma digoxin concentrations and renal glycoside excretion were observed in patients receiving beta-acetyldigoxin and chemotherapy regimens containing cyclophosphamide, vincristine and prednisone with or without cytarabine injection or procarbazine. (label Sitarabin, Interaksi obat)

  • TiagabinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • TopiramatantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

  • ValgansiklovirantivirusModerat

    …associated with myelosuppression or nephrotoxicity (e.g., adriamycin, dapsone, doxorubicin, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/ sulfamethoxazole, vinblastine, vincristine, and zidovudine) Unknown Because of potential for higher toxicity, coadministration with valganciclovir hydrochloride should be considered only if the potential benefits… (label Valgansiklovir, Interaksi obat)

  • VasopresinModerat

    Drugs Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasostrict ® . (label Vasopresin, Interaksi obat)

  • VigabatrinantikonvulsanModerat

    Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. (label Vinkristin, Interaksi obat)

Penyebutan minor (15)

  • Armodafinilstimulan SSPMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • BortezomibMinor

    …baseline for one patient In the combination study of bortezomib with rituximab, cyclophosphamide, doxorubicin and prednisone (BR-CAP) in previously untreated mantle cell lymphoma patients, the incidence of thrombocytopenia (≥ Grade 4) was 32% vs 1% for the rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) arm as shown in Table 12 . (label Bortezomib, Peringatan dan perhatian)

  • Bosentanpenginduksi CYP3A4Minor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Deferasirokssuplemen zat besiMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • DeksametasonkortikosteroidMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • GriseofulvinantijamurMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Lorlatinibpenginduksi CYP3A4Minor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Mitotanpenginduksi CYP3A4Minor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Modafinilstimulan SSPMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Nafsilinantibiotik penisilinMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • NevirapinantiretroviralMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • RifabutinantibiotikMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • RifampisinantibiotikMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • RifapentinantibiotikMinor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

  • Suzetriginpenginduksi CYP3A4Minor

    Concurrent use of strong CYP3A inducers (e.g., St. (label Vinkristin, Interaksi obat)

Periksa Vinkristin terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.