Interaksi Lamotrigin dan Levonorgestrel dan etinilestradiol
Lamotrigin dan Levonorgestrel dan etinilestradiol: kedua label peresepan menguraikan interaksi yang biasanya memerlukan pemantauan, perubahan dosis, atau pemberian jarak antardosis.
Biasanya dapat dikelola dengan pemantauan atau perubahan dosis. Beri tahu apoteker Anda bahwa Anda menggunakan keduanya.
Apa kata label FDA
Dari label Lamotrigin (SUBVENITE) · berlaku sejak 2026-06-04
Decrease in levonorgestrel component by 19%.
Concomitant Use with Estrogen-Containing Products, Including Oral Contraceptives Some estrogen-containing oral contraceptives have been shown to decrease serum concentrations of lamotrigine [see Clinical Pharmacology ( 12.3 )] .
Dosage adjustments will be necessary in most patients who start or stop estrogen-containing oral contraceptives while taking SUBVENITE [see Dosage and Administration ( 2.1 )] .
Estrogen-containing oral contraceptives decrease lamotrigine concentrations by approximately 50%.
Specific dosing guidance for these drugs is provided in the Dosage and Administration section, and, for women taking estrogen-containing products, including oral contraceptives, in the Warnings and Precautions section [see Dosage and Administration ( 2.1 ), Warnings and Precautions ( 5.9 )] .
Dari label Levonorgestrel dan etinilestradiol (Tyblume) · berlaku sejak 2026-08-27
Table 4 Significant Drug Interaction Information for Drugs Co-Administered with CHCs Lamotrigine Clinical effect Concomitant use of CHCs with lamotrigine may significantly decrease systemic exposure of lamotrigine due to induction of lamotrigine glucuronidation [see Clinical Pharmacology (12.3) ].
Decreased systemic exposure of lamotrigine may reduce seizure control.
Consult the approved product labeling for lamotrigine.
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