Cholestyramine and Colestipol interaction

Cholestyramine and Colestipol: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Colestipol (Colestipol Hydrochloride) label · effective 2025-05-13

Moderate

A study has shown that cholestyramine binds bile acids and reduces mycophenolic acid exposure.

Drug interactionsnames CholestyramineView label on DailyMed

From the Cholestyramine label · effective 2026-06-15

Minor

Interference with the absorption of oral phosphate supplements has been observed with another positively-charged bile acid sequestrant.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.