Menthol and methyl salicylate and Sodium phenylacetate and sodium benzoate interaction

Menthol and methyl salicylate and Sodium phenylacetate and sodium benzoate: the Sodium phenylacetate and sodium benzoate prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Sodium phenylacetate and sodium benzoate label · effective 2024-05-09

Moderate

Hyperventilation and Metabolic Acidosis: Sodium Phenylacetate and Sodium Benzoate Injection may cause side effects typically associated with salicylate overdose, such as hyperventilation and metabolic acidosis.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Hyperventilation and Metabolic Acidosis Due to structural similarities between phenylacetate and benzoate to salicylate, Sodium Phenylacetate and Sodium Benzoate Injection may cause side effects typically associated with salicylate overdose, such as hyperventilation and metabolic acidosis.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.