Interações de Demeclociclina
Demeclociclina (Declomycin), antibiótico da classe das tetraciclinas, tem 78 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 14; moderadas: 29; leves: 32; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações graves (14)
Since both acitretin and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see WARNINGS: Pseudotumor Cerebri ). (bula de Acitretina, Contraindicações)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (bula de Isotretinoína, Advertências e precauções)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (bula de Demeclociclina, Interações medicamentosas)
CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the components of the product formulation. (bula de Demeclociclina, Contraindicações)
CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the components of the product formulation. (bula de Demeclociclina, Contraindicações)
Interações moderadas (29)
Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (bula de Acetato de cálcio, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
• Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (bula de Atovaquona, Interações medicamentosas)
• Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (bula de Atovaquona + proguanil, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
O cálcio se liga a esses medicamentos no intestino e pode reduzir drasticamente a quantidade absorvida; separe as doses. (NIH Office of Dietary Supplements, Calcium)
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (bula de Colestipol, Interações medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
O ferro se liga a esses medicamentos no intestino e reduz a sua absorção; separe as doses. (NIH Office of Dietary Supplements, Iron)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (bula de Glimepirida, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (bula de Lantânio, Interações medicamentosas)
- LomitapidaModerada
Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (bula de Lomitapida, Advertências e precauções)
Suplementos e antiácidos que contêm magnésio reduzem a absorção desses medicamentos; separe as doses em pelo menos duas horas. (NIH Office of Dietary Supplements, Magnesium)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (bula de Pioglitazona + glimepirida, Interações medicamentosas)
Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (bula de Quinapril, Interações medicamentosas)
Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (bula de Quinina, Interações medicamentosas)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (bula de Rocurônio, Interações medicamentosas)
- SucralfatoModerada
Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (bula de Sucralfato, Interações medicamentosas)
The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (bula de Tretinoína, Advertências e precauções)
Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (bula de Demeclociclina, Interações medicamentosas)
- VasopressinaModerada
Drugs Suspected of Causing Diabetes Insipidus Use with drugs suspected of causing diabetes insipidus (e.g., demeclocycline, lithium, foscarnet, clozapine) may decrease the pressor effect in addition to the antidiuretic effect of Vasostrict ® . (bula de Vasopressina, Interações medicamentosas)
O zinco reduz a absorção dos antibióticos das classes das quinolonas e das tetraciclinas; tome o antibiótico pelo menos duas horas antes ou quatro a seis horas depois do zinco. (NIH Office of Dietary Supplements, Zinc)
Menções leves (32)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (bula de Demeclociclina, Advertências)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (bula de Demeclociclina, Advertências)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (bula de Demeclociclina, Interações medicamentosas)
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (bula de Demeclociclina, Interações medicamentosas)
WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (bula de Demeclociclina, Advertências)
The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (bula de Vecurônio, Precauções)
Nenhuma interação significativa relatada (3)
…omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (bula de Aminofilina, Interações medicamentosas)
…additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (bula de Cisatracúrio, Interações medicamentosas)
…ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (bula de Teofilina, Interações medicamentosas)
Verifique Demeclociclina com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.