Interaksi Demeklosiklin

Demeklosiklin (Declomycin), golongan antibiotik tetrasiklin, memiliki 78 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 14 mayor, 29 moderat, 32 minor, dan 3 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (14)

  • Amoksisilinantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Amoksisilin dan klavulanatantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Ampisilinantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Ampisilin dan sulbaktamantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • AsitretinretinoidMayor

    Since both acitretin and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see WARNINGS: Pseudotumor Cerebri ). (label Asitretin, Kontraindikasi)

  • Benzilpenisilin (penisilin G)antibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the components of the product formulation. (label Demeklosiklin, Kontraindikasi)

  • Dikloksasilinantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Fenoksimetilpenisilin (penisilin V)antibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • IsotretinoinretinoidMayor

    Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (label Isotretinoin, Peringatan dan perhatian)

  • Nafsilinantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Oksasilinantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Piperasilin dan tazobaktamantibiotik penisilinMayor

    Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (label Demeklosiklin, Interaksi obat)

  • Tetrasiklinantibiotik tetrasiklinMayor

    CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the components of the product formulation. (label Demeklosiklin, Kontraindikasi)

Interaksi moderat (29)

  • ApiksabanantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • ArgatrobanantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • AtovakuonantimalariaModerat

    • Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (label Atovakuon, Interaksi obat)

  • Atovakuon dan proguanilantimalariaModerat

    • Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (label Atovakuon dan proguanil, Interaksi obat)

  • BivalirudinantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • DabigatranantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • EdoksabanantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • EnoksaparinantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • FondaparinuksantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • GlimepiridsulfonilureaModerat

    …antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (label Glimepirid, Interaksi obat)

  • HeparinantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • KalsiumVitamin dan mineralModerat

    Kalsium mengikat obat-obat ini di usus dan dapat sangat mengurangi jumlah yang diserap; pisahkan waktu minum dosisnya. (NIH Office of Dietary Supplements, Calcium)

  • Kalsium asetatpengikat fosfatModerat

    Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (label Kalsium asetat, Interaksi obat)

  • Kolestipolsekuestran asam empeduModerat

    The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (label Kolestipol, Interaksi obat)

  • Kolestiraminsekuestran asam empeduModerat

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (label Kolestiramin, Interaksi obat)

  • Kuinaprilpenghambat ACEModerat

    Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (label Kuinapril, Interaksi obat)

  • KuininantimalariaModerat

    Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (label Kuinin, Interaksi obat)

  • Lantanumpengikat fosfatModerat

    Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (label Lantanum, Interaksi obat)

  • LomitapidModerat

    Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (label Lomitapid, Peringatan dan perhatian)

  • MagnesiumVitamin dan mineralModerat

    Suplemen dan antasida yang mengandung magnesium mengurangi penyerapan obat-obat ini; pisahkan dosisnya dengan jarak setidaknya dua jam. (NIH Office of Dietary Supplements, Magnesium)

  • Pioglitazon dan glimepiridtiazolidindionModerat

    …antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (label Pioglitazon dan glimepirid, Interaksi obat)

  • RivaroksabanantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • Rokuroniumpenyekat neuromuskularModerat

    Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (label Rokuronium, Interaksi obat)

  • SukralfatModerat

    Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (label Sukralfat, Interaksi obat)

  • TretinoinretinoidModerat

    The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (label Tretinoin, Peringatan dan perhatian)

  • VasopresinModerat

    Drugs Suspected of Causing Diabetes Insipidus Use with drugs suspected of causing diabetes insipidus (e.g., demeclocycline, lithium, foscarnet, clozapine) may decrease the pressor effect in addition to the antidiuretic effect of Vasostrict ® . (label Vasopresin, Interaksi obat)

  • WarfarinantikoagulanModerat

    Drug Interactions Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (label Demeklosiklin, Interaksi obat)

  • Zat besiVitamin dan mineralModerat

    Zat besi mengikat obat-obat ini di usus dan mengurangi penyerapannya; pisahkan waktu minum dosisnya. (NIH Office of Dietary Supplements, Iron)

  • Zink (seng)Vitamin dan mineralModerat

    Zink mengurangi penyerapan antibiotik kuinolon dan tetrasiklin; minumlah antibiotik setidaknya dua jam sebelum atau empat sampai enam jam setelah zink. (NIH Office of Dietary Supplements, Zinc)

Penyebutan minor (32)

  • Antasida (Tums, Maalox, Mylanta)Produk obat bebasMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • Deferasirokssuplemen zat besiMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • Deferipronsuplemen zat besiMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • Desogestrel dan etinilestradiolkontrasepsi oralMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Doksisiklinantibiotik tetrasiklinMinor

    WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (label Demeklosiklin, Peringatan)

  • Drospirenon dan etinilestradiolkontrasepsi oralMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • EstradiolestrogenMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Estradiol dan dienogestkontrasepsi oralMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Feri sitratpengikat fosfatMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • FulvestrantestrogenMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • LevonorgestrelprogestinMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • MedroksiprogesteronprogestinMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • MegestrolprogestinMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Mifepristonpenghambat CYP3A4Minor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Minosiklinantibiotik tetrasiklinMinor

    WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (label Demeklosiklin, Peringatan)

  • Natrium bikarbonatantasidaMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • NoretisteronprogestinMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Norgestimat dan etinilestradiolkontrasepsi oralMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Norgestrel dan etinilestradiolkontrasepsi oralMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Omeprazol dan natrium bikarbonatpenghambat pompa protonMinor

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium, and by iron-containing preparations. (label Demeklosiklin, Interaksi obat)

  • ProgesteronprogestinMinor

    Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (label Demeklosiklin, Interaksi obat)

  • Tigesiklinantibiotik tetrasiklinMinor

    WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (label Demeklosiklin, Peringatan)

  • Vekuroniumpenyekat neuromuskularMinor

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (label Vekuronium, Perhatian)

Tidak ada interaksi bermakna yang dilaporkan (3)

  • AminofilinmetilxantinTanpa interaksi

    …omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (label Aminofilin, Interaksi obat)

  • Sisatrakuriumpenyekat neuromuskularTanpa interaksi

    …additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (label Sisatrakurium, Interaksi obat)

  • TeofilinmetilxantinTanpa interaksi

    …ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (label Teofilin, Interaksi obat)

Periksa Demeklosiklin terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.