تداخلات أتراكوريوم
أتراكوريوم (من فئة حاصرات الوصل العصبي العضلي): 64 تداخلًا موثّقًا في نشرات FDA وصحائف الوقائع التي نفهرسها، وتوزيعها: شديدة 8، متوسطة 33، طفيفة 21، وحالات تفيد فيها نشرة بعدم وجود تداخل مهم 2. كل مُدخل أدناه يقتبس الجملة التي يستند إليها. صفحة الدواء هذه نقطة انطلاق، وليست حكمًا على حالتك.
تداخلات من النشرة
تداخلات شديدة (8)
Use of atracurium besylate from multiple dose vials containing benzyl alcohol as a preservative is contraindicated in patients with a known hypersensitivity to benzyl alcohol. (نشرة أتراكوريوم، موانع الاستعمال)
During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (نشرة بلازوميسين، تحذير مؤطر)
Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (نشرة روكورونيوم، موانع الاستعمال)
In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (نشرة ريميفنتانيل، التحذيرات والاحتياطات)
Atracurium should not be administered until a patient has recovered from succinylcholine-induced neuromuscular block. (نشرة أتراكوريوم، التداخلات الدوائية)
- سوغاماديكسشديد
Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (نشرة سوغاماديكس، التحذيرات والاحتياطات)
Avoid concomitant use with neuromuscular blocking agents. (نشرة كينين، التحذيرات والاحتياطات)
The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (نشرة نيومايسين، تحذير مؤطر)
تداخلات متوسطة (33)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (نشرة أتراكوريوم، التحذيرات)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (نشرة أتراكوريوم، التحذيرات)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (نشرة بيبراسيلين وتازوباكتام، التداخلات الدوائية)
Depolarizing neuromuscular blocking agents: Increased effect. (نشرة بيريدوستيغمين، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (نشرة أتراكوريوم، التحذيرات)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
Neuromuscular Blocking Agents Anesthetic concentrations of desflurane at equilibrium (administered for 15 or more minutes before testing) reduced the ED 95 of succinylcholine by approximately 30% and that of atracurium and pancuronium by approximately 50% compared to N 2 O/opioid anesthesia (see Table 4). (نشرة ديسفلوران، التداخلات الدوائية)
Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (نشرة ديفلازاكورت، التحذيرات والاحتياطات)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (نشرة أتراكوريوم، التحذيرات)
When used to supplement alfentanil-N 2 O anesthesia, sevoflurane and isoflurane equally potentiate neuromuscular block induced with pancuronium, vecuronium or atracurium. (نشرة سيفوفلوران، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
• Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (نشرة فنتانيل، التحذيرات والاحتياطات)
Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (نشرة فيراباميل، التداخلات الدوائية)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (نشرة أتراكوريوم، التحذيرات)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
• Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (نشرة كليندامايسين، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (نشرة أتراكوريوم، التداخلات الدوائية)
Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (نشرة لينكومايسين، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (نشرة أتراكوريوم، التداخلات الدوائية)
إشارات طفيفة (21)
Common Neuromuscular Blocking Agents DIPRIVAN does not cause a clinically significant change in onset, intensity or duration of action of the commonly used neuromuscular blocking agents (e.g., succinylcholine and nondepolarizing muscle relaxants). (نشرة بروبوفول، التداخلات الدوائية)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
- دوكسابرامطفيف
In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (نشرة دوكسابرام، التداخلات الدوائية)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (نشرة ديجوكسين، التداخلات الدوائية)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (نشرة فوسفينيتوين، التداخلات الدوائية)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (نشرة فينيتوين، التداخلات الدوائية)
N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (نشرة كاربامازيبين، التداخلات الدوائية)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (نشرة أتراكوريوم، التحذيرات)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (نشرة أتراكوريوم، التحذيرات)
لم يُبلَّغ عن تداخل مهم (2)
Alfentanil and Atracurium Ondansetron does not alter the respiratory depressant effects produced by alfentanil or the degree of neuromuscular blockade produced by atracurium. (نشرة أوندانسيترون، التداخلات الدوائية)
Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (نشرة ديكسميديتوميدين، التداخلات الدوائية)
افحص أتراكوريوم مع كل ما تتناوله. أضف قائمتك كاملة؛ تُفحص كل الأزواج دفعة واحدة.
افتح في الفاحصليست نصيحة طبية. درجة الشدة تعكس صياغة النشرة، لا ظروفك. فالتنبيه «الشديد» قد يكون أمرًا معتادًا تحت الإشراف، والتنبيه «الطفيف» قد يكون مهمًا عند الجرعات العالية. اسأل صيدليًا.