Interaksi Atrakurium

Atrakurium, golongan penyekat neuromuskular, memiliki 64 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 8 mayor, 33 moderat, 21 minor, dan 2 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (8)

  • AlkoholAlkoholMayor

    Use of atracurium besylate from multiple dose vials containing benzyl alcohol as a preservative is contraindicated in patients with a known hypersensitivity to benzyl alcohol. (label Atrakurium, Kontraindikasi)

  • KuininantimalariaMayor

    Avoid concomitant use with neuromuscular blocking agents. (label Kuinin, Peringatan dan perhatian)

  • NeomisinaminoglikosidaMayor

    The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (label Neomisin, Peringatan kotak hitam)

  • PlazomisinaminoglikosidaMayor

    During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (label Plazomisin, Peringatan kotak hitam)

  • RemifentanilopioidMayor

    In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (label Remifentanil, Peringatan dan perhatian)

  • Rokuroniumpenyekat neuromuskularMayor

    Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (label Rokuronium, Kontraindikasi)

  • Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (label Sugamadeks, Peringatan dan perhatian)

  • Suksinilkolinpenyekat neuromuskularMayor

    Atracurium should not be administered until a patient has recovered from succinylcholine-induced neuromuscular block. (label Atrakurium, Interaksi obat)

Interaksi moderat (33)

  • AmikasinaminoglikosidaModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Baklofenpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • Dantrolenpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • DeflazakortkortikosteroidModerat

    Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (label Deflazakort, Peringatan dan perhatian)

  • Dekstrometorfan dan kuinidinobat serotonergikModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Desflurananestetik umumModerat

    Neuromuscular Blocking Agents Anesthetic concentrations of desflurane at equilibrium (administered for 15 or more minutes before testing) reduced the ED 95 of succinylcholine by approximately 30% and that of atracurium and pancuronium by approximately 50% compared to N 2 O/opioid anesthesia (see Table 4). (label Desfluran, Interaksi obat)

  • FentanilopioidModerat

    • Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (label Fentanil, Peringatan dan perhatian)

  • GentamisinaminoglikosidaModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • IncobotulinumtoxinApenyekat neuromuskularModerat

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (label Atrakurium, Peringatan)

  • Isoflurananestetik umumModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Karisoprodolpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • KlindamisinantibiotikModerat

    • Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (label Klindamisin, Interaksi obat)

  • Klorzoksazonpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • KuinidinantiaritmiaModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • LinkomisinantibiotikModerat

    Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (label Linkomisin, Interaksi obat)

  • Litiumobat serotonergikModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • MagnesiumVitamin dan mineralModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Metaksalonpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • Metokarbamolpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • OnabotulinumtoxinApenyekat neuromuskularModerat

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (label Atrakurium, Peringatan)

  • Orfenadrinpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • Piperasilin dan tazobaktamantibiotik penisilinModerat

    Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (label Piperasilin dan tazobaktam, Interaksi obat)

  • Piridostigminpenghambat kolinesteraseModerat

    Depolarizing neuromuscular blocking agents: Increased effect. (label Piridostigmin, Interaksi obat)

  • ProkainamidantiaritmiaModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Sevoflurananestetik umumModerat

    When used to supplement alfentanil-N 2 O anesthesia, sevoflurane and isoflurane equally potentiate neuromuscular block induced with pancuronium, vecuronium or atracurium. (label Sevofluran, Interaksi obat)

  • Siklobenzaprinpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • Sisatrakuriumpenyekat neuromuskularModerat

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (label Atrakurium, Peringatan)

  • Tizanidinpelemas ototModerat

    If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (label Atrakurium, Interaksi obat)

  • TobramisinaminoglikosidaModerat

    Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (label Atrakurium, Interaksi obat)

  • Toksin botulinum tipe Apenyekat neuromuskularModerat

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (label Atrakurium, Peringatan)

  • Vekuroniumpenyekat neuromuskularModerat

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (label Atrakurium, Peringatan)

  • Verapamilpenghambat kanal kalsiumModerat

    Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (label Verapamil, Interaksi obat)

Penyebutan minor (21)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Digoksinglikosida digitalisMinor

    Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (label Digoksin, Interaksi obat)

  • In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (label Doksapram, Interaksi obat)

  • Donepezilpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

  • FenitoinantikonvulsanMinor

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (label Fenitoin, Interaksi obat)

  • FenobarbitalbarbituratMinor

    Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Fisostigminpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

  • FosfenitoinantikonvulsanMinor

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (label Fosfenitoin, Interaksi obat)

  • Galantaminpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

  • KarbamazepinantikonvulsanMinor

    N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (label Karbamazepin, Interaksi obat)

  • Memantin dan donepezilpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

  • MetoheksitalbarbituratMinor

    Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Neostigminpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

  • PrimidonantikonvulsanMinor

    Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (label Atrakurium, Peringatan)

  • Propofoldepresan SSPMinor

    Common Neuromuscular Blocking Agents DIPRIVAN does not cause a clinically significant change in onset, intensity or duration of action of the commonly used neuromuscular blocking agents (e.g., succinylcholine and nondepolarizing muscle relaxants). (label Propofol, Interaksi obat)

  • Rivastigminpenghambat kolinesteraseMinor

    ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (label Atrakurium, Peringatan)

Tidak ada interaksi bermakna yang dilaporkan (2)

  • Deksmedetomidinagonis alfa-adrenergikTanpa interaksi

    Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (label Deksmedetomidin, Interaksi obat)

  • Ondansetronobat yang memperpanjang interval QTTanpa interaksi

    Alfentanil and Atracurium Ondansetron does not alter the respiratory depressant effects produced by alfentanil or the degree of neuromuscular blockade produced by atracurium. (label Ondansetron, Interaksi obat)

Periksa Atrakurium terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.