Interações de Atracúrio
Atracúrio, bloqueador neuromuscular, tem 64 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 8; moderadas: 33; leves: 21; casos em que uma bula relata não haver interação significativa: 2). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações graves (8)
Use of atracurium besylate from multiple dose vials containing benzyl alcohol as a preservative is contraindicated in patients with a known hypersensitivity to benzyl alcohol. (bula de Atracúrio, Contraindicações)
The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (bula de Neomicina, Advertência em caixa preta)
During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (bula de Plazomicina, Advertência em caixa preta)
Avoid concomitant use with neuromuscular blocking agents. (bula de Quinina, Advertências e precauções)
In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (bula de Remifentanila, Advertências e precauções)
Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (bula de Rocurônio, Contraindicações)
- SugamadexGrave
Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (bula de Sugamadex, Advertências e precauções)
Atracurium should not be administered until a patient has recovered from succinylcholine-induced neuromuscular block. (bula de Atracúrio, Interações medicamentosas)
Interações moderadas (33)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Atracúrio, Advertências)
• Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (bula de Clindamicina, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (bula de Deflazacorte, Advertências e precauções)
Neuromuscular Blocking Agents Anesthetic concentrations of desflurane at equilibrium (administered for 15 or more minutes before testing) reduced the ED 95 of succinylcholine by approximately 30% and that of atracurium and pancuronium by approximately 50% compared to N 2 O/opioid anesthesia (see Table 4). (bula de Desflurano, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
• Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (bula de Fentanila, Advertências e precauções)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (bula de Lincomicina, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (bula de Piperacilina + tazobactam, Interações medicamentosas)
Depolarizing neuromuscular blocking agents: Increased effect. (bula de Piridostigmina, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
When used to supplement alfentanil-N 2 O anesthesia, sevoflurane and isoflurane equally potentiate neuromuscular block induced with pancuronium, vecuronium or atracurium. (bula de Sevoflurano, Interações medicamentosas)
If other muscle relaxants are used during the same procedure, the possibility of a synergistic or antagonist effect should be considered. (bula de Atracúrio, Interações medicamentosas)
Drug Interactions Drugs which may enhance the neuromuscular blocking action of atracurium include: enflurane; isoflurane; halothane; certain antibiotics, especially the aminoglycosides and polymyxins; lithium; magnesium salts; procainamide; and quinidine. (bula de Atracúrio, Interações medicamentosas)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Atracúrio, Advertências)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Atracúrio, Advertências)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Atracúrio, Advertências)
Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (bula de Atracúrio, Advertências)
Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (bula de Verapamil, Interações medicamentosas)
Menções leves (21)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (bula de Carbamazepina, Interações medicamentosas)
Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (bula de Digoxina, Interações medicamentosas)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
- DoxapramLeve
In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (bula de Doxapram, Interações medicamentosas)
Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (bula de Fenitoína, Interações medicamentosas)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (bula de Fosfenitoína, Interações medicamentosas)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
Atracurium besylate injection, which has an acid pH, should not be mixed with alkaline solutions (e.g., barbiturate solutions) in the same syringe or administered simultaneously during intravenous infusion through the same needle. (bula de Atracúrio, Advertências)
Common Neuromuscular Blocking Agents DIPRIVAN does not cause a clinically significant change in onset, intensity or duration of action of the commonly used neuromuscular blocking agents (e.g., succinylcholine and nondepolarizing muscle relaxants). (bula de Propofol, Interações medicamentosas)
ANTICHOLINESTERASE REVERSAL AGENTS SHOULD BE IMMEDIATELY AVAILABLE. (bula de Atracúrio, Advertências)
Nenhuma interação significativa relatada (2)
Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (bula de Dexmedetomidina, Interações medicamentosas)
Alfentanil and Atracurium Ondansetron does not alter the respiratory depressant effects produced by alfentanil or the degree of neuromuscular blockade produced by atracurium. (bula de Ondansetrona, Interações medicamentosas)
Verifique Atracúrio com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.