تداخلات فينتولامين
فينتولامين (OraVerse، Regitine؛ من فئة حاصرات ألفا): 47 تداخلًا موثّقًا في نشرات FDA وصحائف الوقائع التي نفهرسها، وتوزيعها: شديدة 8، متوسطة 28، طفيفة 10، وحالات تفيد فيها نشرة بعدم وجود تداخل مهم 1. كل مُدخل أدناه يقتبس الجملة التي يستند إليها. صفحة الدواء هذه نقطة انطلاق، وليست حكمًا على حالتك.
تداخلات من النشرة
تداخلات شديدة (8)
Should not be used in combination with other alpha adrenergic antagonists ( 5.4 , 7.2 ) (نشرة ألفوزوسين، التحذيرات والاحتياطات)
…that Affect Concomitant Drug Concentrations Concomitant Drug Within Class Prevention or Management Drug Interactions with TOLSURA that Increase Concomitant Drug Concentrations and May Increase Risk of Adverse Reactions Associated with the Concomitant Drug Alpha Blockers Alfuzosin Silodosin Tamsulosin Not recommended during and 2 weeks after TOLSURA treatment. (نشرة إيتراكونازول، التداخلات الدوائية)
Avoid coadministration of FANAPT with alpha-adrenergic blocking agents and adjust medications that affect blood pressure as needed [see Warnings and Precautions (5.7) ] . (نشرة إيلوبيريدون، التداخلات الدوائية)
CIALIS is not recommended in combination with alpha-blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. (نشرة تادالافيل، التحذيرات والاحتياطات)
• Should not be used in combination with other alpha adrenergic blocking agents ( 5.2 , 7.2 , 12.3 ) (نشرة تامسولوسين، التحذيرات والاحتياطات)
Do not use JALYN with other alpha-adrenergic antagonists, as this may increase the risk of hypotension. (نشرة دوتاستيريد وتامسولوسين، التحذيرات والاحتياطات)
Silodosin capsules should not be used in combination with other alpha-blockers. (نشرة سيلودوسين، التحذيرات والاحتياطات)
(The dosage reported for phentolamine is 5 mg intravenously.) Care should be taken to administer this drug slowly in order to avoid producing an excessive hypotensive effect. (نشرة فينيلزين، التحذيرات)
تداخلات متوسطة (28)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (نشرة أفانافيل، التحذيرات والاحتياطات)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Alpha Blockers: Co-administration of beta-blockers with alpha-blocker (e.g., prazosin) has been associated with prolongation of first dose hypotension and syncope. (نشرة بروبرانولول، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
As with other alpha-blockers, there is a potential for syncope, especially after the initial dose or after an increase in dosage strength. (نشرة دوكسازوسين، التحذيرات والاحتياطات)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (نشرة سيلدينافيل، التحذيرات والاحتياطات)
- غلوكاغونمتوسط
If the patient develops a substantial increase in blood pressure and a previously undiagnosed pheochromocytoma is suspected, 5 to 10 mg of phentolamine mesylate, administered intravenously, has been shown to be effective in lowering blood pressure. (نشرة غلوكاغون، التحذيرات والاحتياطات)
Alpha-Blockers : Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers. (نشرة فاردينافيل، التحذيرات والاحتياطات)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Alpha Blockers tamsulosin Analgesics methadone alfentanil, buprenorphine IV and sublingual, fentanyl, oxycodone, sufentanil Methadone: The potential increase in plasma concentrations of methadone when coadministered with ketoconazole tablets may increase the risk of serious cardiovascular events including QT prolongation and torsade de pointes, or respiratory… (نشرة كيتوكونازول، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
- ميتيروسينمتوسط
Intraoperative Effects While the preoperative use of metyrosine capsules in patients with pheochromocytoma is thought to decrease intraoperative problems with blood pressure control, metyrosine does not eliminate the danger of hypertensive crises or arrhythmias during manipulation of the tumor, and the alpha-adrenergic blocking drug, phentolamine, may be needed. (نشرة ميتيروسين، التحذيرات)
Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (نشرة فينتولامين، التداخلات الدوائية)
Central Alpha1-Blockers Doxazosin: Healthy volunteers participating in a multiple dose doxazosin-nifedipine interaction study received 2 mg doxazosin q.d. alone or combined with 20 mg nifedipine ER b.i.d. Co-administration of nifedipine resulted in a decrease in AUC and C max of doxazosin to 83% and 86% of the values in the absence of nifedipine, respectively. (نشرة نيفيديبين، التداخلات الدوائية)
إشارات طفيفة (10)
Use in Patients with Pheochromocytoma If BREVIBLOC injection is used in the setting of pheochromocytoma, give it in combination with an alpha-blocker, and only after the alpha-blocker has been initiated. (نشرة إسمولول، التحذيرات والاحتياطات)
Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (نشرة فينتولامين، التحذيرات والاحتياطات)
Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (نشرة فينتولامين، التحذيرات والاحتياطات)
Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (نشرة فينتولامين، التحذيرات والاحتياطات)
Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (نشرة فينتولامين، التحذيرات والاحتياطات)
If rebound hypertension occurs, reverse hypertensive crisis with oral clonidine or IV phentolamine. (نشرة كلونيدين، التحذيرات والاحتياطات)
Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (نشرة فينتولامين، التحذيرات والاحتياطات)
Pheochromocytoma: Initiate therapy with an alpha blocker. (نشرة ميتوبرولول، التحذيرات والاحتياطات)
Pheochromocytoma: First initiate therapy with an alpha blocker. (نشرة ميتوبرولول وهيدروكلوروثيازيد، التحذيرات والاحتياطات)
Alpha-adrenergic blocking agents, such as prazosin, terazosin, and doxazosin, can antagonize the effects of midodrine hydrochloride. (نشرة ميدودرين، التداخلات الدوائية)
لم يُبلَّغ عن تداخل مهم (1)
Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (نشرة دوتاستيريد، التداخلات الدوائية)
افحص فينتولامين مع كل ما تتناوله. أضف قائمتك كاملة؛ تُفحص كل الأزواج دفعة واحدة.
افتح في الفاحصليست نصيحة طبية. درجة الشدة تعكس صياغة النشرة، لا ظروفك. فالتنبيه «الشديد» قد يكون أمرًا معتادًا تحت الإشراف، والتنبيه «الطفيف» قد يكون مهمًا عند الجرعات العالية. اسأل صيدليًا.