Interacciones de Fentolamina

Fentolamina (OraVerse, Regitine), alfabloqueante, tiene 47 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 8; moderadas: 28; leves: 10; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 1. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (8)

  • AlfuzosinaalfabloqueanteGrave

    Should not be used in combination with other alpha adrenergic antagonists ( 5.4 , 7.2 ) (etiqueta de Alfuzosina, Advertencias y precauciones)

  • Dutasterida y tamsulosinainhibidor de la 5-alfa reductasaGrave

    Do not use JALYN with other alpha-adrenergic antagonists, as this may increase the risk of hypotension. (etiqueta de Dutasterida y tamsulosina, Advertencias y precauciones)

  • Fenelzinainhibidor de la MAOGrave

    (The dosage reported for phentolamine is 5 mg intravenously.) Care should be taken to administer this drug slowly in order to avoid producing an excessive hypotensive effect. (etiqueta de Fenelzina, Advertencias)

  • IloperidonaantipsicóticoGrave

    Avoid coadministration of FANAPT with alpha-adrenergic blocking agents and adjust medications that affect blood pressure as needed [see Warnings and Precautions (5.7) ] . (etiqueta de Iloperidona, Interacciones medicamentosas)

  • Itraconazolantifúngico azólicoGrave

    …that Affect Concomitant Drug Concentrations Concomitant Drug Within Class Prevention or Management Drug Interactions with TOLSURA that Increase Concomitant Drug Concentrations and May Increase Risk of Adverse Reactions Associated with the Concomitant Drug Alpha Blockers Alfuzosin Silodosin Tamsulosin Not recommended during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)

  • SilodosinaalfabloqueanteGrave

    Silodosin capsules should not be used in combination with other alpha-blockers. (etiqueta de Silodosina, Advertencias y precauciones)

  • Tadalafiloinhibidor de la PDE5Grave

    CIALIS is not recommended in combination with alpha-blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. (etiqueta de Tadalafilo, Advertencias y precauciones)

  • TamsulosinaalfabloqueanteGrave

    • Should not be used in combination with other alpha adrenergic blocking agents ( 5.2 , 7.2 , 12.3 ) (etiqueta de Tamsulosina, Advertencias y precauciones)

Interacciones moderadas (28)

  • AdrenalinasimpaticomiméticoModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Articaína y adrenalinaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Avanafiloinhibidor de la PDE5Moderada

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)

  • Bupivacaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Bupivacaína y adrenalinaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Cloroprocaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Cocaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Desfluranoanestésico generalModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • DoxazosinaalfabloqueanteModerada

    As with other alpha-blockers, there is a potential for syncope, especially after the initial dose or after an increase in dosage strength. (etiqueta de Doxazosina, Advertencias y precauciones)

  • Etomidatoanestésico generalModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • GlucagónModerada

    If the patient develops a substantial increase in blood pressure and a previously undiagnosed pheochromocytoma is suspected, 5 to 10 mg of phentolamine mesylate, administered intravenously, has been shown to be effective in lowering blood pressure. (etiqueta de Glucagón, Advertencias y precauciones)

  • Isofluranoanestésico generalModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Ketaminadepresor del SNCModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Ketoconazolantifúngico azólicoModerada

    Alpha Blockers tamsulosin Analgesics methadone alfentanil, buprenorphine IV and sublingual, fentanyl, oxycodone, sufentanil Methadone: The potential increase in plasma concentrations of methadone when coadministered with ketoconazole tablets may increase the risk of serious cardiovascular events including QT prolongation and torsade de pointes, or respiratory… (etiqueta de Ketoconazol, Interacciones medicamentosas)

  • Lidocaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Lidocaína y adrenalinaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Lidocaína y prilocaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Mepivacaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • MetirosinaModerada

    Intraoperative Effects While the preoperative use of metyrosine capsules in patients with pheochromocytoma is thought to decrease intraoperative problems with blood pressure control, metyrosine does not eliminate the danger of hypertensive crises or arrhythmias during manipulation of the tumor, and the alpha-adrenergic blocking drug, phentolamine, may be needed. (etiqueta de Metirosina, Advertencias)

  • MetohexitalbarbitúricoModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Central Alpha1-Blockers Doxazosin: Healthy volunteers participating in a multiple dose doxazosin-nifedipine interaction study received 2 mg doxazosin q.d. alone or combined with 20 mg nifedipine ER b.i.d. Co-administration of nifedipine resulted in a decrease in AUC and C max of doxazosin to 83% and 86% of the values in the absence of nifedipine, respectively. (etiqueta de Nifedipino, Interacciones medicamentosas)

  • Prilocaína y adrenalinaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Propofoldepresor del SNCModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • PropranololbetabloqueanteModerada

    Alpha Blockers: Co-administration of beta-blockers with alpha-blocker (e.g., prazosin) has been associated with prolongation of first dose hypotension and syncope. (etiqueta de Propranolol, Interacciones medicamentosas)

  • Ropivacaínaanestésico localModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Sevofluranoanestésico generalModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (etiqueta de Fentolamina, Interacciones medicamentosas)

  • Sildenafiloinhibidor de la PDE5Moderada

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)

  • Vardenafiloinhibidor de la PDE5Moderada

    Alpha-Blockers : Caution is advised when PDE5 inhibitors are co-administered with alpha-blockers. (etiqueta de Vardenafilo, Advertencias y precauciones)

Menciones leves (10)

  • CarvedilolbetabloqueanteLeve

    Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (etiqueta de Fentolamina, Advertencias y precauciones)

  • Clonidinaagonista alfa-adrenérgicoLeve

    If rebound hypertension occurs, reverse hypertensive crisis with oral clonidine or IV phentolamine. (etiqueta de Clonidina, Advertencias y precauciones)

  • EsmololbetabloqueanteLeve

    Use in Patients with Pheochromocytoma If BREVIBLOC injection is used in the setting of pheochromocytoma, give it in combination with an alpha-blocker, and only after the alpha-blocker has been initiated. (etiqueta de Esmolol, Advertencias y precauciones)

  • FenoxibenzaminaalfabloqueanteLeve

    Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (etiqueta de Fentolamina, Advertencias y precauciones)

  • LabetalolbetabloqueanteLeve

    Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (etiqueta de Fentolamina, Advertencias y precauciones)

  • MetoprololbetabloqueanteLeve

    Pheochromocytoma: Initiate therapy with an alpha blocker. (etiqueta de Metoprolol, Advertencias y precauciones)

  • Pheochromocytoma: First initiate therapy with an alpha blocker. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

  • Midodrinaagonista alfa-adrenérgicoLeve

    Alpha-adrenergic blocking agents, such as prazosin, terazosin, and doxazosin, can antagonize the effects of midodrine hydrochloride. (etiqueta de Midodrina, Interacciones medicamentosas)

  • PrazosinaalfabloqueanteLeve

    Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (etiqueta de Fentolamina, Advertencias y precauciones)

  • TerazosinaalfabloqueanteLeve

    Tachycardia and cardiac arrhythmiasmay occur with the use of phentolamine or other alpha-adrenergic blocking agents. (etiqueta de Fentolamina, Advertencias y precauciones)

Sin interacción significativa según la etiqueta (1)

  • Dutasteridainhibidor de la 5-alfa reductasaSin interacción

    Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist. (etiqueta de Dutasterida, Interacciones medicamentosas)

Compruebe Fentolamina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.