تداخلات الكافيين

Use of methylxanthines (e.g., caffeine, aminophylline and theophylline) is not recommended in patients who experience a seizures in association with adenosine injection ( 5.6 ) (نشرة أدينوزين، التحذيرات والاحتياطات)

CONTRAINDICATIONS Pentoxifylline extended-release tablets should not be used in patients with recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine. (نشرة بنتوكسيفيلين، موانع الاستعمال)

…hot dogs, breakfast sausage, and cooked sliced ham) Vegetables Broad bean pods (fava bean pods) All other vegetables Dairy Aged cheeses Processed cheeses, mozzarella, ricotta cheese, cottage cheese, and yogurt Beverages All varieties of tap beer and beers that have not been pasteurized so as to allow for ongoing fermentation and excessive amounts of caffeine. (نشرة ترانيلسيبرومين، التداخلات الدوائية)

Excessive amounts of caffeine and chocolate may also cause hypertensive reactions. (نشرة فينيلزين، موانع الاستعمال)

Terbinafine decreases the clearance of caffeine by 19%. (نشرة تيربينافين، التداخلات الدوائية)

Agents Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered. (نشرة ديفيراسيروكس، التداخلات الدوائية)

Co-administration of ciprofloxacin and other drugs primarily metabolized by CYP1A2 (for example, theophylline, methylxanthines, caffeine, tizanidine, ropinirole, clozapine, olanzapine and zolpidem), results in increased plasma concentrations of the co-administered drug and could lead to clinically significant pharmacodynamic adverse reactions of the co-administered… (نشرة سيبروفلوكساسين، التحذيرات والاحتياطات)

Additionally, in one controlled study in five normal subjects and seven patients, the clearance of caffeine was decreased 50% following the administration of mexiletine. (نشرة ميكسيليتين، التداخلات الدوائية)

…metronidazole, miconazole, oxandrolone, sulfinpyrazone, tigecycline, voriconazole, zafirlukast aprepitant, bosentan, carbamazepine, phenobarbital, rifampin CYP1A2 acyclovir, allopurinol, caffeine, cimetidine, ciprofloxacin, disulfiram, enoxacin, famotidine, fluvoxamine, methoxsalen, mexiletine, norfloxacin, oral contraceptives, phenylpropanolamine, propafenone, propranolol,… (نشرة وارفارين، التداخلات الدوائية)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (نشرة أمينوفيلين، التداخلات الدوائية)

Caffeine Interactions between ofloxacin and caffeine have not been detected. (نشرة أوفلوكساسين، التداخلات الدوائية)

No relevant interactions with substrates for CYP 2A6 (warfarin), CYP 1A2 (caffeine), CYP 3A4 (midazolam, terfenadine, cyclosporine), CYP 2C19 (S-mephenytoin) and CYP 2D6 (desipramine) were observed in vitro. (نشرة تولكابون، التداخلات الدوائية)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (نشرة ثيوفيلين، التداخلات الدوائية)

This finding was confirmed in vivo by a clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, a CYP1A2 substrate. (نشرة فينلافاكسين، التداخلات الدوائية)

Moderate or weak CYP1A2 inhibitors include oral contraceptives and caffeine. (نشرة كلوزابين، التداخلات الدوائية)

Conversely, the pharmacokinetics of quinidine are not significantly affected by caffeine, ciprofloxacin, digoxin, felodipine, omeprazole, or quinine . (نشرة كينيدين، التداخلات الدوائية)

…Clinically Important Interaction with Noxafil and Noxafil PowderMix Additional clinical studies demonstrated that no clinically important effects on zidovudine, lamivudine, indinavir, or caffeine were observed when administered with Noxafil 200 mg once daily; therefore, no dose adjustments are required for these drugs when coadministered with Noxafil 200 mg once daily. (نشرة بوساكونازول، التداخلات الدوائية)