Interacciones de Cafeína
La cafeína es un estimulante que se elimina mediante la enzima CYP1A2; los fármacos que bloquean esa enzima pueden hacer que el café tenga un efecto mucho más intenso.
Cafeína tiene 17 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 4; moderadas: 5; leves: 7; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 1. Cada entrada de abajo cita la frase que la respalda. Esta página, de la categoría «Alimentos y bebidas», es un punto de partida, no un veredicto sobre su situación.
Interacciones según la etiqueta
Interacciones graves (4)
Use of methylxanthines (e.g., caffeine, aminophylline and theophylline) is not recommended in patients who experience a seizures in association with adenosine injection ( 5.6 ) (etiqueta de Adenosina, Advertencias y precauciones)
Excessive amounts of caffeine and chocolate may also cause hypertensive reactions. (etiqueta de Fenelzina, Contraindicaciones)
CONTRAINDICATIONS Pentoxifylline extended-release tablets should not be used in patients with recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine. (etiqueta de Pentoxifilina, Contraindicaciones)
…hot dogs, breakfast sausage, and cooked sliced ham) Vegetables Broad bean pods (fava bean pods) All other vegetables Dairy Aged cheeses Processed cheeses, mozzarella, ricotta cheese, cottage cheese, and yogurt Beverages All varieties of tap beer and beers that have not been pasteurized so as to allow for ongoing fermentation and excessive amounts of caffeine. (etiqueta de Tranilcipromina, Interacciones medicamentosas)
Interacciones moderadas (5)
Co-administration of ciprofloxacin and other drugs primarily metabolized by CYP1A2 (for example, theophylline, methylxanthines, caffeine, tizanidine, ropinirole, clozapine, olanzapine and zolpidem), results in increased plasma concentrations of the co-administered drug and could lead to clinically significant pharmacodynamic adverse reactions of the co-administered… (etiqueta de Ciprofloxacino, Advertencias y precauciones)
Agents Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered. (etiqueta de Deferasirox, Interacciones medicamentosas)
Additionally, in one controlled study in five normal subjects and seven patients, the clearance of caffeine was decreased 50% following the administration of mexiletine. (etiqueta de Mexiletina, Interacciones medicamentosas)
Terbinafine decreases the clearance of caffeine by 19%. (etiqueta de Terbinafina, Interacciones medicamentosas)
…metronidazole, miconazole, oxandrolone, sulfinpyrazone, tigecycline, voriconazole, zafirlukast aprepitant, bosentan, carbamazepine, phenobarbital, rifampin CYP1A2 acyclovir, allopurinol, caffeine, cimetidine, ciprofloxacin, disulfiram, enoxacin, famotidine, fluvoxamine, methoxsalen, mexiletine, norfloxacin, oral contraceptives, phenylpropanolamine, propafenone, propranolol,… (etiqueta de Warfarina, Interacciones medicamentosas)
Menciones leves (7)
Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (etiqueta de Aminofilina, Interacciones medicamentosas)
Moderate or weak CYP1A2 inhibitors include oral contraceptives and caffeine. (etiqueta de Clozapina, Interacciones medicamentosas)
Caffeine Interactions between ofloxacin and caffeine have not been detected. (etiqueta de Ofloxacino, Interacciones medicamentosas)
Conversely, the pharmacokinetics of quinidine are not significantly affected by caffeine, ciprofloxacin, digoxin, felodipine, omeprazole, or quinine . (etiqueta de Quinidina, Interacciones medicamentosas)
Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (etiqueta de Teofilina, Interacciones medicamentosas)
- TolcaponaLeve
No relevant interactions with substrates for CYP 2A6 (warfarin), CYP 1A2 (caffeine), CYP 3A4 (midazolam, terfenadine, cyclosporine), CYP 2C19 (S-mephenytoin) and CYP 2D6 (desipramine) were observed in vitro. (etiqueta de Tolcapona, Interacciones medicamentosas)
This finding was confirmed in vivo by a clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, a CYP1A2 substrate. (etiqueta de Venlafaxina, Interacciones medicamentosas)
Sin interacción significativa según la etiqueta (1)
…Clinically Important Interaction with Noxafil and Noxafil PowderMix Additional clinical studies demonstrated that no clinically important effects on zidovudine, lamivudine, indinavir, or caffeine were observed when administered with Noxafil 200 mg once daily; therefore, no dose adjustments are required for these drugs when coadministered with Noxafil 200 mg once daily. (etiqueta de Posaconazol, Interacciones medicamentosas)
Compruebe Cafeína frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.
Abrir en el verificadorNo es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.