Wechselwirkungen von Koffein

Use of methylxanthines (e.g., caffeine, aminophylline and theophylline) is not recommended in patients who experience a seizures in association with adenosine injection ( 5.6 ) (Fachinformation zu Adenosin, Warnhinweise und Vorsichtsmaßnahmen)

CONTRAINDICATIONS Pentoxifylline extended-release tablets should not be used in patients with recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine. (Fachinformation zu Pentoxifyllin, Gegenanzeigen)

Excessive amounts of caffeine and chocolate may also cause hypertensive reactions. (Fachinformation zu Phenelzin, Gegenanzeigen)

…hot dogs, breakfast sausage, and cooked sliced ham) Vegetables Broad bean pods (fava bean pods) All other vegetables Dairy Aged cheeses Processed cheeses, mozzarella, ricotta cheese, cottage cheese, and yogurt Beverages All varieties of tap beer and beers that have not been pasteurized so as to allow for ongoing fermentation and excessive amounts of caffeine. (Fachinformation zu Tranylcypromin, Arzneimittelwechselwirkungen)

Co-administration of ciprofloxacin and other drugs primarily metabolized by CYP1A2 (for example, theophylline, methylxanthines, caffeine, tizanidine, ropinirole, clozapine, olanzapine and zolpidem), results in increased plasma concentrations of the co-administered drug and could lead to clinically significant pharmacodynamic adverse reactions of the co-administered… (Fachinformation zu Ciprofloxacin, Warnhinweise und Vorsichtsmaßnahmen)

Agents Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered. (Fachinformation zu Deferasirox, Arzneimittelwechselwirkungen)

Additionally, in one controlled study in five normal subjects and seven patients, the clearance of caffeine was decreased 50% following the administration of mexiletine. (Fachinformation zu Mexiletin, Arzneimittelwechselwirkungen)

Terbinafine decreases the clearance of caffeine by 19%. (Fachinformation zu Terbinafin, Arzneimittelwechselwirkungen)

…metronidazole, miconazole, oxandrolone, sulfinpyrazone, tigecycline, voriconazole, zafirlukast aprepitant, bosentan, carbamazepine, phenobarbital, rifampin CYP1A2 acyclovir, allopurinol, caffeine, cimetidine, ciprofloxacin, disulfiram, enoxacin, famotidine, fluvoxamine, methoxsalen, mexiletine, norfloxacin, oral contraceptives, phenylpropanolamine, propafenone, propranolol,… (Fachinformation zu Warfarin, Arzneimittelwechselwirkungen)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (Fachinformation zu Aminophyllin, Arzneimittelwechselwirkungen)

Conversely, the pharmacokinetics of quinidine are not significantly affected by caffeine, ciprofloxacin, digoxin, felodipine, omeprazole, or quinine . (Fachinformation zu Chinidin, Arzneimittelwechselwirkungen)

Moderate or weak CYP1A2 inhibitors include oral contraceptives and caffeine. (Fachinformation zu Clozapin, Arzneimittelwechselwirkungen)

Caffeine Interactions between ofloxacin and caffeine have not been detected. (Fachinformation zu Ofloxacin, Arzneimittelwechselwirkungen)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (Fachinformation zu Theophyllin, Arzneimittelwechselwirkungen)

No relevant interactions with substrates for CYP 2A6 (warfarin), CYP 1A2 (caffeine), CYP 3A4 (midazolam, terfenadine, cyclosporine), CYP 2C19 (S-mephenytoin) and CYP 2D6 (desipramine) were observed in vitro. (Fachinformation zu Tolcapon, Arzneimittelwechselwirkungen)

This finding was confirmed in vivo by a clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, a CYP1A2 substrate. (Fachinformation zu Venlafaxin, Arzneimittelwechselwirkungen)

…Clinically Important Interaction with Noxafil and Noxafil PowderMix Additional clinical studies demonstrated that no clinically important effects on zidovudine, lamivudine, indinavir, or caffeine were observed when administered with Noxafil 200 mg once daily; therefore, no dose adjustments are required for these drugs when coadministered with Noxafil 200 mg once daily. (Fachinformation zu Posaconazol, Arzneimittelwechselwirkungen)