कैफीन के इंटरैक्शन

Use of methylxanthines (e.g., caffeine, aminophylline and theophylline) is not recommended in patients who experience a seizures in association with adenosine injection ( 5.6 ) (एडेनोसिन लेबल, चेतावनियां और सावधानियां)

…hot dogs, breakfast sausage, and cooked sliced ham) Vegetables Broad bean pods (fava bean pods) All other vegetables Dairy Aged cheeses Processed cheeses, mozzarella, ricotta cheese, cottage cheese, and yogurt Beverages All varieties of tap beer and beers that have not been pasteurized so as to allow for ongoing fermentation and excessive amounts of caffeine. (ट्रैनिलसाइप्रोमिन लेबल, दवाओं के इंटरैक्शन)

CONTRAINDICATIONS Pentoxifylline extended-release tablets should not be used in patients with recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine. (पेंटोक्सिफाइलिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Excessive amounts of caffeine and chocolate may also cause hypertensive reactions. (फेनेलज़िन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Terbinafine decreases the clearance of caffeine by 19%. (टर्बिनाफिन लेबल, दवाओं के इंटरैक्शन)

Agents Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered. (डेफेरासिरोक्स लेबल, दवाओं के इंटरैक्शन)

Additionally, in one controlled study in five normal subjects and seven patients, the clearance of caffeine was decreased 50% following the administration of mexiletine. (मेक्सिलेटिन लेबल, दवाओं के इंटरैक्शन)

…metronidazole, miconazole, oxandrolone, sulfinpyrazone, tigecycline, voriconazole, zafirlukast aprepitant, bosentan, carbamazepine, phenobarbital, rifampin CYP1A2 acyclovir, allopurinol, caffeine, cimetidine, ciprofloxacin, disulfiram, enoxacin, famotidine, fluvoxamine, methoxsalen, mexiletine, norfloxacin, oral contraceptives, phenylpropanolamine, propafenone, propranolol,… (वारफेरिन लेबल, दवाओं के इंटरैक्शन)

Co-administration of ciprofloxacin and other drugs primarily metabolized by CYP1A2 (for example, theophylline, methylxanthines, caffeine, tizanidine, ropinirole, clozapine, olanzapine and zolpidem), results in increased plasma concentrations of the co-administered drug and could lead to clinically significant pharmacodynamic adverse reactions of the co-administered… (सिप्रोफ्लॉक्सासिन लेबल, चेतावनियां और सावधानियां)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (एमिनोफाइलिन लेबल, दवाओं के इंटरैक्शन)

Caffeine Interactions between ofloxacin and caffeine have not been detected. (ओफ्लॉक्सासिन लेबल, दवाओं के इंटरैक्शन)

Moderate or weak CYP1A2 inhibitors include oral contraceptives and caffeine. (क्लोज़ापिन लेबल, दवाओं के इंटरैक्शन)

Conversely, the pharmacokinetics of quinidine are not significantly affected by caffeine, ciprofloxacin, digoxin, felodipine, omeprazole, or quinine . (क्विनिडिन लेबल, दवाओं के इंटरैक्शन)

No relevant interactions with substrates for CYP 2A6 (warfarin), CYP 1A2 (caffeine), CYP 3A4 (midazolam, terfenadine, cyclosporine), CYP 2C19 (S-mephenytoin) and CYP 2D6 (desipramine) were observed in vitro. (टोलकैपोन लेबल, दवाओं के इंटरैक्शन)

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays. (थियोफाइलिन लेबल, दवाओं के इंटरैक्शन)

This finding was confirmed in vivo by a clinical drug interaction study in which venlafaxine did not inhibit the metabolism of caffeine, a CYP1A2 substrate. (वेनलाफैक्सिन लेबल, दवाओं के इंटरैक्शन)

…Clinically Important Interaction with Noxafil and Noxafil PowderMix Additional clinical studies demonstrated that no clinically important effects on zidovudine, lamivudine, indinavir, or caffeine were observed when administered with Noxafil 200 mg once daily; therefore, no dose adjustments are required for these drugs when coadministered with Noxafil 200 mg once daily. (पोसाकोनाज़ोल लेबल, दवाओं के इंटरैक्शन)