Wechselwirkungen von Bexaroten
Bexaroten (Targretin), ein Retinoid, hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 58 dokumentierte Wechselwirkungen: 5 schwerwiegende, 27 mittelschwere, 26 geringfügige und 0, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.
Wechselwirkungen laut Fachinformation
Schwerwiegende Wechselwirkungen (5)
Acitretin is contraindicated in cases of hypersensitivity (e.g., angioedema, urticaria) to the preparation (acitretin or excipients) or to other retinoids . (Fachinformation zu Acitretin, Gegenanzeigen)
Because of a potential drug-drug interaction, avoid gemfibrozil use with TARGRETIN [ see Drug Interactions (7) ]. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Avoid concomitant use of isotretinoin and EMROSI because isotretinoin, a systemic retinoid, is also known to cause idiopathic intracranial hypertension. (Fachinformation zu Minocyclin, Warnhinweise und Vorsichtsmaßnahmen)
Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (Fachinformation zu Tetracyclin, Warnhinweise)
Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (Fachinformation zu Tretinoin, Gegenanzeigen)
Mittelschwere Wechselwirkungen (27)
Patients with CTCL who have risk factors for pancreatitis (e.g., prior pancreatitis, uncontrolled hyperlipidemia, excessive alcohol consumption, uncontrolled diabetes mellitus, biliary tract disease, and medications known to increase triglyceride levels or to be associated with pancreatic toxicity) may be at greater risk for pancreatitis associated with TARGRETIN… (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
- CalciumchloridMittelschwer
Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (Fachinformation zu Calciumchlorid, Arzneimittelwechselwirkungen)
- Elexacaftor, Tezacaftor und IvacaftorMittelschwer
Patients with elevated vitamin A levels may be at increased risk. (Fachinformation zu Elexacaftor, Tezacaftor und Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Patients with elevated vitamin A levels may be at increased risk. (Fachinformation zu Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor patients receiving XATMEP with other potential hepatotoxins (e.g., azathioprine, retinoids, and sulfasalazine) for possible signs of hepatotoxicity. (Fachinformation zu Methotrexat, Arzneimittelwechselwirkungen)
- OrlistatMittelschwer
The effect of ORLISTAT on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time [see Clinical Pharmacology (12.3) , and Warnings and Precautions (5.1) ] . (Fachinformation zu Orlistat, Arzneimittelwechselwirkungen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Monitor and replace thyroid hormone if needed. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Geringfügige Erwähnungen (26)
Atorvastatin was used in 48% (73/152) of patients with CTCL. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
Atorvastatin was used in 48% (73/152) of patients with CTCL. (Fachinformation zu Bexaroten, Warnhinweise und Vorsichtsmaßnahmen)
- CalciumgluconatGeringfügig
Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (Fachinformation zu Calciumgluconat, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Vitamin A Based on a case report in one patient receiving combination therapy with all-trans-retinoid acid (an acid form of vitamin A) and fluconazole, central nervous system (CNS) related undesirable effects have developed in the form of pseudotumor cerebri, which disappeared after discontinuation of fluconazole treatment. (Fachinformation zu Fluconazol, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
Drug products which may be affected include oral or other systemic hormonal contraceptives. (Fachinformation zu Bexaroten, Arzneimittelwechselwirkungen)
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Im Wechselwirkungscheck öffnenKeine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.