Interaksi Beksaroten

Beksaroten (Targretin), golongan retinoid, memiliki 58 interaksi terdokumentasi dalam label FDA dan lembar fakta yang kami indeks: 5 mayor, 27 moderat, 26 minor, dan 0 dengan label yang melaporkan tidak ada interaksi bermakna. Setiap entri di bawah ini mengutip kalimat yang mendasarinya. Halaman obat ini adalah titik awal, bukan putusan untuk situasi Anda.

Interaksi dari label

Interaksi mayor (5)

  • AsitretinretinoidMayor

    Acitretin is contraindicated in cases of hypersensitivity (e.g., angioedema, urticaria) to the preparation (acitretin or excipients) or to other retinoids . (label Asitretin, Kontraindikasi)

  • GemfibrozilfibratMayor

    Because of a potential drug-drug interaction, avoid gemfibrozil use with TARGRETIN [ see Drug Interactions (7) ]. (label Beksaroten, Peringatan dan perhatian)

  • Minosiklinantibiotik tetrasiklinMayor

    Avoid concomitant use of isotretinoin and EMROSI because isotretinoin, a systemic retinoid, is also known to cause idiopathic intracranial hypertension. (label Minosiklin, Peringatan dan perhatian)

  • Tetrasiklinantibiotik tetrasiklinMayor

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (label Tetrasiklin, Peringatan)

  • TretinoinretinoidMayor

    Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (label Tretinoin, Kontraindikasi)

Interaksi moderat (27)

  • AlkoholAlkoholModerat

    Patients with CTCL who have risk factors for pancreatitis (e.g., prior pancreatitis, uncontrolled hyperlipidemia, excessive alcohol consumption, uncontrolled diabetes mellitus, biliary tract disease, and medications known to increase triglyceride levels or to be associated with pancreatic toxicity) may be at greater risk for pancreatitis associated with TARGRETIN… (label Beksaroten, Peringatan dan perhatian)

  • Patients with elevated vitamin A levels may be at increased risk. (label Eleksakaftor, tezakaftor, dan ivakaftor, Peringatan dan perhatian)

  • GlibenklamidsulfonilureaModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Glibenklamid dan metforminsulfonilureaModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • GlimepiridsulfonilureaModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • GlipizidsulfonilureaModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Glipizid dan metforminsulfonilureaModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Insulin aspartinsulinModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Insulin degludekinsulinModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Insulin detemirinsulinModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Insulin glargininsulinModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Insulin lisproinsulinModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Ivakaftorpenghambat CYP3A4Moderat

    Patients with elevated vitamin A levels may be at increased risk. (label Ivakaftor, Peringatan dan perhatian)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (label Kalsium klorida, Interaksi obat)

  • Levotiroksinhormon tiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • Levotiroksin dan liotironinhormon tiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • Liotironinhormon tiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • MetotreksatimunosupresanModerat

    Monitor patients receiving XATMEP with other potential hepatotoxins (e.g., azathioprine, retinoids, and sulfasalazine) for possible signs of hepatotoxicity. (label Metotreksat, Interaksi obat)

  • OrlistatModerat

    The effect of ORLISTAT on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time [see Clinical Pharmacology (12.3) , and Warnings and Precautions (5.1) ] . (label Orlistat, Interaksi obat)

  • PioglitazontiazolidindionModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Pioglitazon dan glimepiridtiazolidindionModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Pioglitazon dan metformintiazolidindionModerat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

  • Propiltiourasilobat antitiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • Teriparatidhormon tiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • Tiamazolobat antitiroidModerat

    Monitor and replace thyroid hormone if needed. (label Beksaroten, Peringatan dan perhatian)

  • Tirzepatidagonis reseptor GLP-1Moderat

    Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (label Beksaroten, Peringatan dan perhatian)

Penyebutan minor (26)

  • Amlodipin dan atorvastatinpenghambat kanal kalsium dihidropiridinMinor

    Atorvastatin was used in 48% (73/152) of patients with CTCL. (label Beksaroten, Peringatan dan perhatian)

  • AtorvastatinstatinMinor

    Atorvastatin was used in 48% (73/152) of patients with CTCL. (label Beksaroten, Peringatan dan perhatian)

  • Desogestrel dan etinilestradiolkontrasepsi oralMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drospirenon dan etinilestradiolkontrasepsi oralMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • EstradiolestrogenMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Estradiol dan dienogestkontrasepsi oralMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Flukonazolantijamur azolMinor

    Vitamin A Based on a case report in one patient receiving combination therapy with all-trans-retinoid acid (an acid form of vitamin A) and fluconazole, central nervous system (CNS) related undesirable effects have developed in the form of pseudotumor cerebri, which disappeared after discontinuation of fluconazole treatment. (label Flukonazol, Interaksi obat)

  • FulvestrantestrogenMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (label Kalsium glukonat, Interaksi obat)

  • LevonorgestrelprogestinMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • MedroksiprogesteronprogestinMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • MegestrolprogestinMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Mifepristonpenghambat CYP3A4Minor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • NoretisteronprogestinMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Norgestimat dan etinilestradiolkontrasepsi oralMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • Norgestrel dan etinilestradiolkontrasepsi oralMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

  • ProgesteronprogestinMinor

    Drug products which may be affected include oral or other systemic hormonal contraceptives. (label Beksaroten, Interaksi obat)

Periksa Beksaroten terhadap semua yang Anda gunakan. Tambahkan seluruh daftar Anda; setiap pasangan diperiksa sekaligus.

Buka di pemeriksa

Bukan nasihat medis. Tingkat keparahan mencerminkan kata-kata dalam label, bukan keadaan Anda. Tanda “mayor” bisa merupakan hal yang rutin di bawah pengawasan, dan tanda “minor” bisa menjadi penting pada dosis tinggi. Tanyakan kepada apoteker.