Interações de Bexaroteno

Acitretin is contraindicated in cases of hypersensitivity (e.g., angioedema, urticaria) to the preparation (acitretin or excipients) or to other retinoids . (bula de Acitretina, Contraindicações)

Because of a potential drug-drug interaction, avoid gemfibrozil use with TARGRETIN [ see Drug Interactions (7) ]. (bula de Bexaroteno, Advertências e precauções)

Avoid concomitant use of isotretinoin and EMROSI because isotretinoin, a systemic retinoid, is also known to cause idiopathic intracranial hypertension. (bula de Minociclina, Advertências e precauções)

Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (bula de Tetraciclina, Advertências)

Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. (bula de Tretinoína, Contraindicações)

Patients with CTCL who have risk factors for pancreatitis (e.g., prior pancreatitis, uncontrolled hyperlipidemia, excessive alcohol consumption, uncontrolled diabetes mellitus, biliary tract disease, and medications known to increase triglyceride levels or to be associated with pancreatic toxicity) may be at greater risk for pancreatitis associated with TARGRETIN… (bula de Bexaroteno, Advertências e precauções)

Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (bula de Cloreto de cálcio, Interações medicamentosas)

Patients with elevated vitamin A levels may be at increased risk. (bula de Elexacaftor + tezacaftor + ivacaftor, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Patients with elevated vitamin A levels may be at increased risk. (bula de Ivacaftor, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Monitor patients receiving XATMEP with other potential hepatotoxins (e.g., azathioprine, retinoids, and sulfasalazine) for possible signs of hepatotoxicity. (bula de Metotrexato, Interações medicamentosas)

The effect of ORLISTAT on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time [see Clinical Pharmacology (12.3) , and Warnings and Precautions (5.1) ] . (bula de Orlistate, Interações medicamentosas)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

Hypoglycemia Risk in Patients with Diabetes Mellitus In patients using insulin, agents enhancing insulin secretion (e.g., sulfonylureas), or insulin sensitizers (e.g., thiazolidinedione class), based on the mechanism of action, TARGRETIN could enhance the action of these agents, resulting in hypoglycemia. (bula de Bexaroteno, Advertências e precauções)

Atorvastatin was used in 48% (73/152) of patients with CTCL. (bula de Bexaroteno, Advertências e precauções)

Atorvastatin was used in 48% (73/152) of patients with CTCL. (bula de Bexaroteno, Advertências e precauções)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Vitamin A Based on a case report in one patient receiving combination therapy with all-trans-retinoid acid (an acid form of vitamin A) and fluconazole, central nervous system (CNS) related undesirable effects have developed in the form of pseudotumor cerebri, which disappeared after discontinuation of fluconazole treatment. (bula de Fluconazol, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (bula de Gliconato de cálcio, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)

Drug products which may be affected include oral or other systemic hormonal contraceptives. (bula de Bexaroteno, Interações medicamentosas)