Wechselwirkungen von Tigecyclin

Since both acitretin and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see WARNINGS: Pseudotumor Cerebri ). (Fachinformation zu Acitretin, Gegenanzeigen)

Drug Interactions Bacteriostatic antibacterials ( i.e. , chloramphenicol, erythromycins, sulfonamides or tetracyclines) may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (Fachinformation zu Benzylpenicillin (Penicillin G), Arzneimittelwechselwirkungen)

Avoid use in patients with known hypersensitivity to tetracyclines. (Fachinformation zu Tigecyclin, Warnhinweise und Vorsichtsmaßnahmen)

Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (Fachinformation zu Isotretinoin, Warnhinweise und Vorsichtsmaßnahmen)

Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Avoid use in patients with known hypersensitivity to tetracyclines. (Fachinformation zu Tigecyclin, Warnhinweise und Vorsichtsmaßnahmen)

• Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (Fachinformation zu Atovaquon, Arzneimittelwechselwirkungen)

• Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (Fachinformation zu Atovaquon und Proguanil, Arzneimittelwechselwirkungen)

Calcium bindet diese Arzneistoffe im Darm und kann die aufgenommene Menge stark verringern; die Dosen zeitlich getrennt einnehmen. (NIH Office of Dietary Supplements, Calcium)

Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (Fachinformation zu Calciumacetat, Arzneimittelwechselwirkungen)

Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (Fachinformation zu Chinin, Arzneimittelwechselwirkungen)

The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (Fachinformation zu Colestipol, Arzneimittelwechselwirkungen)

Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (Fachinformation zu Colestyramin, Arzneimittelwechselwirkungen)

Eisen bindet diese Arzneistoffe im Darm und verringert ihre Aufnahme; die Dosen zeitlich getrennt einnehmen. (NIH Office of Dietary Supplements, Iron)

…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (Fachinformation zu Glimepirid, Arzneimittelwechselwirkungen)

Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (Fachinformation zu Lanthancarbonat, Arzneimittelwechselwirkungen)

Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (Fachinformation zu Lomitapid, Warnhinweise und Vorsichtsmaßnahmen)

Magnesiumhaltige Präparate und Antazida verringern die Aufnahme dieser Arzneistoffe; die Dosen im Abstand von mindestens zwei Stunden einnehmen. (NIH Office of Dietary Supplements, Magnesium)

…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (Fachinformation zu Pioglitazon und Glimepirid, Arzneimittelwechselwirkungen)

Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (Fachinformation zu Quinapril, Arzneimittelwechselwirkungen)

Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (Fachinformation zu Rocuronium, Arzneimittelwechselwirkungen)

Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (Fachinformation zu Sucralfat, Arzneimittelwechselwirkungen)

The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (Fachinformation zu Tretinoin, Warnhinweise und Vorsichtsmaßnahmen)

• Warfarin : Suitable anticoagulation test should be monitored if TYGACIL is administered to patients receiving warfarin. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Zink verringert die Aufnahme von Chinolon- und Tetracyclin-Antibiotika; das Antibiotikum mindestens zwei Stunden vor oder vier bis sechs Stunden nach Zink einnehmen. (NIH Office of Dietary Supplements, Zinc)

Other Antibacterials Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effects of penicillin. (Fachinformation zu Amoxicillin, Arzneimittelwechselwirkungen)

Bacteriostatic Antibiotics : Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. (Fachinformation zu Ampicillin, Arzneimittelwechselwirkungen)

WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (Fachinformation zu Demeclocyclin, Warnhinweise)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin and concurrent use of these drugs should be avoided. (Fachinformation zu Dicloxacillin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Other Interactions Digitalis, tetracyclines, nicotine, or antihistamines, or intravenous nitroglycerin may partially counteract the anticoagulant action of heparin sodium. (Fachinformation zu Heparin, Arzneimittelwechselwirkungen)

In cIAI studies (n=1642), 6 patients treated with TYGACIL and 2 patients treated with imipenem/cilastatin presented with intestinal perforations and developed sepsis/septic shock. (Fachinformation zu Tigecyclin, Warnhinweise und Vorsichtsmaßnahmen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (Fachinformation zu Nafcillin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin and concurrent use of these drugs should be avoided. (Fachinformation zu Oxacillin, Arzneimittelwechselwirkungen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (Fachinformation zu Vecuronium, Vorsichtsmaßnahmen)

Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (Fachinformation zu Tigecyclin, Arzneimittelwechselwirkungen)

…omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (Fachinformation zu Aminophyllin, Arzneimittelwechselwirkungen)

…additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (Fachinformation zu Cisatracurium, Arzneimittelwechselwirkungen)

…ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (Fachinformation zu Theophyllin, Arzneimittelwechselwirkungen)