Interacciones de Tigeciclina
Tigeciclina (Tygacil), antibiótico del grupo de las tetraciclinas, tiene 61 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 8; moderadas: 19; leves: 31; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 3. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.
Interacciones según la etiqueta
Interacciones graves (8)
Since both acitretin and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated (see WARNINGS: Pseudotumor Cerebri ). (etiqueta de Acitretina, Contraindicaciones)
Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Intracranial Hypertension ( Pseudotumor Cerebri ): Avoid concomitant use with tetracyclines ( 5.5 ) (etiqueta de Isotretinoína, Advertencias y precauciones)
Drug Interactions Bacteriostatic antibacterials ( i.e. , chloramphenicol, erythromycins, sulfonamides or tetracyclines) may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (etiqueta de Penicilina G, Interacciones medicamentosas)
Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Avoid use in patients with known hypersensitivity to tetracyclines. (etiqueta de Tigeciclina, Advertencias y precauciones)
Therefore, serum concentrations of the calcineurin inhibitor should be monitored during treatment with TYGACIL to avoid drug toxicity. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Avoid use in patients with known hypersensitivity to tetracyclines. (etiqueta de Tigeciclina, Advertencias y precauciones)
Interacciones moderadas (19)
Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (etiqueta de Acetato de calcio, Interacciones medicamentosas)
• Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (etiqueta de Atovacuona, Interacciones medicamentosas)
• Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (etiqueta de Atovacuona y proguanil, Interacciones medicamentosas)
El calcio se une a estos fármacos en el intestino y puede reducir drásticamente la cantidad que se absorbe; separe las dosis. (NIH Office of Dietary Supplements, Calcium)
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (etiqueta de Colestipol, Interacciones medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etiqueta de Colestiramina, Interacciones medicamentosas)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (etiqueta de Glimepirida, Interacciones medicamentosas)
El hierro se une a estos fármacos en el intestino y reduce su absorción; separe las dosis. (NIH Office of Dietary Supplements, Iron)
Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (etiqueta de Lantano, Interacciones medicamentosas)
- LomitapidaModerada
Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (etiqueta de Lomitapida, Advertencias y precauciones)
Los suplementos y los antiácidos que contienen magnesio reducen la absorción de estos fármacos; separe las dosis al menos dos horas. (NIH Office of Dietary Supplements, Magnesium)
…antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (etiqueta de Pioglitazona y glimepirida, Interacciones medicamentosas)
Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (etiqueta de Quinapril, Interacciones medicamentosas)
Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (etiqueta de Quinina, Interacciones medicamentosas)
Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (etiqueta de Rocuronio, Interacciones medicamentosas)
- SucralfatoModerada
Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (etiqueta de Sucralfato, Interacciones medicamentosas)
The concomitant use of other products (e.g., tetracyclines) that can cause intracranial hypertension may increase the risk. (etiqueta de Tretinoína, Advertencias y precauciones)
• Warfarin : Suitable anticoagulation test should be monitored if TYGACIL is administered to patients receiving warfarin. (etiqueta de Tigeciclina, Interacciones medicamentosas)
El zinc reduce la absorción de los antibióticos del grupo de las quinolonas y de las tetraciclinas; tome el antibiótico al menos dos horas antes o de cuatro a seis horas después del zinc. (NIH Office of Dietary Supplements, Zinc)
Menciones leves (31)
Other Antibacterials Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effects of penicillin. (etiqueta de Amoxicilina, Interacciones medicamentosas)
Bacteriostatic Antibiotics : Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. (etiqueta de Ampicilina, Interacciones medicamentosas)
WARNINGS DEMECLOCYCLINE HYDROCHLORIDE, LIKE OTHER TETRACYCLINE-CLASS ANTIBIOTICS, CAN CAUSE FETAL HARM WHEN ADMINISTERED TO A PREGNANT WOMAN. (etiqueta de Demeclociclina, Advertencias)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin and concurrent use of these drugs should be avoided. (etiqueta de Dicloxacilina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Other Interactions Digitalis, tetracyclines, nicotine, or antihistamines, or intravenous nitroglycerin may partially counteract the anticoagulant action of heparin sodium. (etiqueta de Heparina, Interacciones medicamentosas)
In cIAI studies (n=1642), 6 patients treated with TYGACIL and 2 patients treated with imipenem/cilastatin presented with intestinal perforations and developed sepsis/septic shock. (etiqueta de Tigeciclina, Advertencias y precauciones)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (etiqueta de Nafcilina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin and concurrent use of these drugs should be avoided. (etiqueta de Oxacilina, Interacciones medicamentosas)
Oral Contraceptives Concurrent use of antibacterial drugs with oral contraceptives may render oral contraceptives less effective. (etiqueta de Tigeciclina, Interacciones medicamentosas)
The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (etiqueta de Vecuronio, Precauciones)
Sin interacción significativa según la etiqueta (3)
…omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (etiqueta de Aminofilina, Interacciones medicamentosas)
…additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (etiqueta de Cisatracurio, Interacciones medicamentosas)
…ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (etiqueta de Teofilina, Interacciones medicamentosas)
Compruebe Tigeciclina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.
Abrir en el verificadorNo es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.