Interaction Checker

Interacciones de Protamina

Protamina tiene 81 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 51; moderadas: 26; leves: 0; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 4. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (51)

  • AcebutololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Ácido aminocaproicoantifibrinolíticoGrave

    • Protamine paracoagulation test is positive in DIC; a precipitate forms when protamine sulfate is dropped into citrated plasma. (etiqueta de Ácido aminocaproico, Contraindicaciones)

  • AdrenalinasimpaticomiméticoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Anfepramonaestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Articaína y adrenalinaanestésico localGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • AtenololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Atenolol y clortalidonabetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Benzfetaminaestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • BetaxololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • BisoprololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Bisoprolol e hidroclorotiazidabetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Brimonidina y timololagonista alfa-adrenérgicoGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Bromfeniramina, pseudoefedrina y dextrometorfanoantihistamínicoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Bupivacaína y adrenalinaanestésico localGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • CarvedilolbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • DobutaminasimpaticomiméticoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Dorzolamida y timololinhibidor de la anhidrasa carbónicaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • DroxidopasimpaticomiméticoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • EfedrinasimpaticomiméticoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • EnoxaparinaanticoagulanteGrave

    Protamine sulfate should not be given when bleeding occurs without prior heparin use. (etiqueta de Protamina, Advertencia en recuadro)

  • EsmololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Fendimetrazinaestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • FenilefrinadescongestionanteGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Fenterminaestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • HeparinaanticoagulanteGrave

    Protamine sulfate should not be given when bleeding occurs without prior heparin use. (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina aspartainsulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina degludecinsulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina detemirinsulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina glarginainsulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina lisproinsulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Insulina regular (humana)insulinaGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • LabetalolbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Lidocaína y adrenalinaanestésico localGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Metanfetaminaestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • MetoprololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Metoprolol e hidroclorotiazidabetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Midodrinaagonista alfa-adrenérgicoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Mirabegrónagonista beta-adrenérgicoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • Modafiniloestimulante del SNCGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • NadololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • NebivololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • OximetazolinadescongestionanteGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • PindololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Prilocaína y adrenalinaanestésico localGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • PropranololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • PseudoefedrinadescongestionanteGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

  • SotalolbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • TimololbetabloqueanteGrave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Tirzepatidaagonista del receptor de GLP-1Grave

    Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (etiqueta de Protamina, Advertencia en recuadro)

  • Vibegrónagonista beta-adrenérgicoGrave

    Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine. (etiqueta de Protamina, Advertencia en recuadro)

Interacciones moderadas (26)

  • Amoxicilinaantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Amoxicilina y ácido clavulánicoantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Ampicilinaantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Ampicilina y sulbactamantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefaclorcefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefadroxilocefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefalexinacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefazolinacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefdinircefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefepimacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefiximacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefotaximacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefotetáncefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefoxitinacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefpodoximacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefprozilocefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CeftarolinacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CeftriaxonacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • CefuroximacefalosporinaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Dicloxacilinaantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Nafcilinaantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Oxacilinaantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Penicilina Gantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Penicilina Vantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

  • Piperacilina y tazobactamantibiótico del grupo de las penicilinasModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (etiqueta de Protamina, Precauciones)

Sin interacción significativa según la etiqueta (4)

  • ApixabánanticoagulanteSin interacción

    Protamine sulfate and vitamin K are not expected to affect the anticoagulant activity of apixaban. (etiqueta de Apixabán, Advertencias y precauciones)

  • DabigatránanticoagulanteSin interacción

    Protamine sulfate and vitamin K are not expected to affect the anticoagulant activity of dabigatran. (etiqueta de Dabigatrán, Advertencias y precauciones)

  • EdoxabánanticoagulanteSin interacción

    Protamine sulfate, vitamin K, and tranexamic acid are not expected to reverse the anticoagulant activity of SAVAYSA. (etiqueta de Edoxabán, Advertencias y precauciones)

  • RivaroxabánanticoagulanteSin interacción

    Protamine sulfate and vitamin K are not expected to affect the anticoagulant activity of rivaroxaban. (etiqueta de Rivaroxabán, Advertencias y precauciones)

Compruebe Protamina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.