Interações de Escitalopram

Escitalopram (Lexapro), ISRS, tem 349 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 119; moderadas: 189; leves: 38; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

O escitalopram é um antidepressivo ISRS vendido como Lexapro e amplamente como genérico. É a forma única ativa do citalopram, um medicamento mais antigo, e aumenta a quantidade de serotonina disponível no cérebro. É aprovado para depressão maior em pessoas a partir de 12 anos e para transtorno de ansiedade generalizada em pessoas a partir de 7 anos. É apresentado em comprimido e geralmente é tomado uma vez ao dia, de manhã ou à noite, com ou sem alimentos.

Interações segundo a bula

Interações graves (119)

  • ÁlcoolÁlcoolGrave

    Alcohol Prevention or Management Concomitant use of Escitalopram Capsules and alcohol is not recommended. (bula de Escitalopram, Interações medicamentosas)

  • AlmotriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • AmiodaronaantiarrítmicoGrave

    Reserve the combination of amiodarone with other antiarrhythmic therapies that prolong the QTc to patients with life-threatening ventricular arrhythmias who are incompletely responsive to a single agent. (bula de Amiodarona, Advertências e precauções)

  • Amitriptilinaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Amoxapinaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Anfetaminaestimulante do SNCGrave

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (bula de Anfetamina, Advertências e precauções)

  • Anfetamina + dextroanfetaminaestimulante do SNCGrave

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans), but also during overdosage situations. (bula de Anfetamina + dextroanfetamina, Advertências e precauções)

  • Azitromicinaantibiótico macrolídeoGrave

    This risk which can be fatal should be considered in patients with certain cardiovascular disorders including known QT prolongation or history torsades de pointes, those with proarrhythmic conditions, and with other drugs that prolong the QT interval. (bula de Azitromicina, Advertências e precauções)

  • Azul de metilenoinibidor da MAOGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • Beladona + ópioopioideGrave

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (bula de Beladona + ópio, Interações medicamentosas)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • BuprenorfinaopioideGrave

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Buprenorfina, Interações medicamentosas)

  • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (bula de Buprenorfina + naloxona, Interações medicamentosas)

  • Buspironamedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Intervention: Avoid concomitant use Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Butalbital + ácido acetilsalicílico + cafeína + codeína, Interações medicamentosas)

  • • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (bula de Butalbital + paracetamol + cafeína + codeína, Interações medicamentosas)

  • ButorfanolopioideGrave

    …medical attention if they ‎experience symptoms of hyperalgesia, including worsening pain, increased ‎sensitivity to pain, or new pain [see WARNINGS ; ADVERSE REACTIONS ].‎ Serotonin Syndrome Inform patients that butorphanol tartrate could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Butorfanol, Precauções)

  • CarbamazepinaanticonvulsivanteGrave

    Known hypersensitivity to tricyclic antidepressants ( 4 ) (bula de Carbamazepina, Contraindicações)

  • Ciclobenzaprinarelaxante muscularGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • CiprofloxacinofluoroquinolonaGrave

    Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval. (bula de Ciprofloxacino, Advertências e precauções)

  • CitalopramISRSGrave

    With known hypersensitivity to escitalopram or citalopram or any of the inactive ingredients in Escitalopram Capsules. (bula de Escitalopram, Contraindicações)

  • Clomipraminaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • CodeínaopioideGrave

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (bula de Codeína, Interações medicamentosas)

  • Desipraminaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Dextroanfetaminaestimulante do SNCGrave

    Serotonergic Drugs The concomitant use of dextroamphetamine sulfate and serotonergic drugs increases the risk of serotonin syndrome. (bula de Dextroanfetamina, Interações medicamentosas)

  • Dextrometorfanomedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Dextrometorfano + quinidinamedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Di-hidroergotaminaalcaloide do ergotGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • DofetilidaantiarrítmicoGrave

    Use with Drugs that Prolong QT Interval and Antiarrhythmic Agents The use of dofetilide in conjunction with other drugs that prolong the QT interval has not been studied and is not recommended. (bula de Dofetilida, Advertências)

  • Doxepinaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • DronedaronaantiarrítmicoGrave

    …(12.3) ] • Concomitant use of drugs or herbal products that prolong the QT interval and might increase the risk of torsade de pointes, such as phenothiazine antipsychotics, tricyclic antidepressants, certain oral macrolide antibiotics, and Class I and III antiarrhythmics • Liver or lung toxicity related to the previous use of amiodarone • QTc interval >500 ms or… (bula de Dronedarona, Contraindicações)

  • DuloxetinaIRSNGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • EdoxabanaanticoagulanteGrave

    Anticoagulants, Antiplatelets, Thrombolytics, and Selective Serotonin Reuptake Inhibitors (SSRIs)/Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Avoid concomitant use due to increased risk of bleeding. (bula de Edoxabana, Interações medicamentosas)

  • EletriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Concomitant use of COMPLERA with drugs with a known risk to prolong the QTc interval of the electrocardiogram may increase the risk of Torsade de Pointes. (bula de Entricitabina + rilpivirina + tenofovir, Advertências e precauções)

  • Erva-de-são-joão (hipérico)Fitoterápicos e suplementosGrave

    Combinar a erva-de-são-joão (hipérico) com antidepressivos e outros medicamentos serotoninérgicos aumenta o risco de síndrome serotoninérgica. (NCCIH, St. John's Wort)

  • Fenelzinainibidor da MAOGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • FenobarbitalbarbitúricoGrave

    Drugs that Prolong the QT Interval : Avoid concomitant use. (bula de Fenobarbital, Interações medicamentosas)

  • FentanilaopioideGrave

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (bula de Fentanila, Advertências e precauções)

  • Flibanserinadepressor do SNCGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Fluconazolantifúngico azólicoGrave

    Coadministration of other drugs known to prolong the QT interval and which are metabolized via the enzyme CYP3A4 such as erythromycin, pimozide, and quinidine are contraindicated in patients receiving fluconazole. (bula de Fluconazol, Contraindicações)

  • FlumazenilbenzodiazepínicoGrave

    THESE ARE MOST FREQUENT IN PATIENTS WHO HAVE BEEN ON BENZODIAZEPINES FOR LONG-TERM SEDATION OR IN OVERDOSE CASES WHERE PATIENTS ARE SHOWING SIGNS OF SERIOUS CYCLIC ANTIDEPRESSANT OVERDOSE. (bula de Flumazenil, Advertência em caixa preta)

  • FluoxetinaISRSGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • FluvoxaminaISRSGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • FoscarneteantiviralGrave

    (See DOSAGE and ADMINISTRATION. ) Because of the risk of QT prolongation and the potential for torsades de pointes, the use of FOSCAVIR should be avoided in combination with agents known to prolong the QT interval including Class IA (e.g., quinidine or procainamide) or Class III (e.g., dofetilide, amiodarone, sotalol) antiarrhythmic agents, phenothiazines, tricyclic… (bula de Foscarnete, Interações medicamentosas)

  • FosfomicinaantibióticoGrave

    Avoid co-administration of CONTEPO with drugs known to prolong the QT interval. (bula de Fosfomicina, Interações medicamentosas)

  • FrovatriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Granisetronamedicamento que prolonga o intervalo QTGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • HidrocodonaopioideGrave

    Example: lactulose Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Hidrocodona, Interações medicamentosas)

  • Serotonergic drugs : Concomitant use may result in serotonin syndrome. (bula de Hidrocodona + clorfeniramina, Interações medicamentosas)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Hidrocodona + homatropina, Interações medicamentosas)

  • S er otonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Hidrocodona + ibuprofeno, Precauções)

  • Serotonin Syndrome Inform patients that hydrocodone bitartrate and acetaminophen tablets could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Hidrocodona + paracetamol, Precauções)

  • HidromorfonaopioideGrave

    • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Hidromorfona, Interações medicamentosas)

  • Hidroxicloroquinamedicamento que prolonga o intervalo QTGrave

    Therefore, PLAQUENIL is not recommended in patients taking other drugs that have the potential to prolong the QT interval. (bula de Hidroxicloroquina, Advertências e precauções)

  • IloperidonaantipsicóticoGrave

    Avoid the use of FANAPT in combination with any other drugs that prolong the QT interval [see Warnings and Precautions (5.3) ] . (bula de Iloperidona, Interações medicamentosas)

  • Imipraminaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • IsoniazidaantibióticoGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • Bradycardia may increase the risk of QT prolongation which may lead to severe ventricular arrhythmias, including torsade de pointes, especially in patients with risk factors such as use of QTc prolonging drugs [see Adverse Reactions ( 6.2 )] . (bula de Ivabradina, Advertências e precauções)

  • LevofloxacinofluoroquinolonaGrave

    Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval ( 5.11 , 8.5 ) (bula de Levofloxacino, Advertências e precauções)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • LevorfanolopioideGrave

    Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Levorfanol, Precauções)

  • LinezolidaantibióticoGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • Lisdexanfetaminaestimulante do SNCGrave

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (bula de Lisdexanfetamina, Advertências e precauções)

  • Lítiomedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Lopinavir + ritonavirantirretroviralGrave

    Avoid use in patients with congenital long QT syndrome, those with hypokalemia, and with other drugs that prolong the QT interval. (bula de Lopinavir + ritonavir, Advertências e precauções)

  • LorazepambenzodiazepínicoGrave

    LOREEV XR should not be used in such patients without adequate antidepressant therapy. (bula de Lorazepam, Advertências e precauções)

  • MetadonaopioideGrave

    Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (bula de Metadona, Advertências e precauções)

  • Metanfetaminaestimulante do SNCGrave

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (bula de Metanfetamina, Advertências e precauções)

  • Metaxalonarelaxante muscularGrave

    Serotonin syndrome has resulted from concomitant use of metaxalone (within the recommended dosage range) and other serotonergic drugs [see Warnings and Precautions (5.1) ]. (bula de Metaxalona, Interações medicamentosas)

  • MilnacipranaIRSNGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • MirtazapinaantidepressivoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • MorfinaopioideGrave

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (bula de Morfina, Interações medicamentosas)

  • NaratriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • NefazodonaantidepressivoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Nortriptilinaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Olanzapina + fluoxetinaantipsicóticoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • OliceridinaopioideGrave

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Oliceridina, Interações medicamentosas)

  • Ondansetronamedicamento que prolonga o intervalo QTGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Avoid coadministration of oxaliplatin injection with medicinal products with a known potential to prolong the QT interval. (bula de Oxaliplatina, Interações medicamentosas)

  • OxicodonaopioideGrave

    Serotonergic Drug s: Concomitant use may result in serotonin syndrome. (bula de Oxicodona, Interações medicamentosas)

  • OximorfonaopioideGrave

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Oximorfona, Interações medicamentosas)

  • Palonosetronamedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Paracetamol + codeína, Precauções)

  • ParoxetinaISRSGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (bula de Pentazocina + naloxona, Precauções)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • PimozidaantipsicóticoGrave

    Taking pimozide because of the risk of QT prolongation [see Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • Pitolisantomedicamento que prolonga o intervalo QTGrave

    The use of WAKIX should be avoided in patients with known QT prolongation or in combination with other drugs known to prolong the QT interval [see Drug Interactions ( 7.1 )]. (bula de Pitolisanto, Advertências e precauções)

  • Prometazinaanti-histamínicoGrave

    …prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. (bula de Prometazina, Interações medicamentosas)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (bula de Prometazina + codeína, Interações medicamentosas)

  • Prometazina + dextrometorfanoanti-histamínicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • PropafenonaantiarrítmicoGrave

    • Avoid use with other antiarrhythmic agents or drugs that prolong the QT interval. (bula de Propafenona, Advertências e precauções)

  • Protriptilinaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Prucalopridamedicamento serotoninérgicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Rasagilinainibidor da MAOGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • RemifentanilaopioideGrave

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (bula de Remifentanila, Advertências e precauções)

  • RizatriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Selegilinainibidor da MAOGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • SertralinaISRSGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Solriamfetolestimulante do SNCGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • SumatriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • TapentadolopioideGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Tetrabenazinainibidor do VMAT2Grave

    Certain conditions may increase the risk for torsade de pointes or sudden death such as (1) bradycardia; (2) hypokalemia or hypomagnesemia; (3) concomitant use of other drugs that prolong the QTc interval; and (4) presence of congenital prolongation of the QT interval [see Warnings and Precautions ( 5.8 ), Clinical Pharmacology (12.2) ]. (bula de Tetrabenazina, Interações medicamentosas)

  • TioridazinaantipsicóticoGrave

    CONTRAINDICATIONS Thioridazine hydrochloride tablet use should be avoided in combination with other drugs that are known to prolong the QTc interval and in patients with congenital long QT syndrome or a history of cardiac arrhythmias. (bula de Tioridazina, Contraindicações)

  • TramadolopioideGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Tranilciprominainibidor da MAOGrave

    Escitalopram Capsules are contraindicated in patients: Taking, or within 14 days of stopping, MAOIs, including linezolid or intravenous methylene blue, because of an increased risk of serotonin syndrome [see Dosage and Administration ( 2.6 ), Warnings and Precautions ( 5.2 ), Drug Interactions ( 7 )] . (bula de Escitalopram, Contraindicações)

  • TrazodonaantidepressivoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Trimipraminaantidepressivo tricíclicoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • VenlafaxinaIRSNGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • Avoid concomitant use of VEPPANU with strong CYP3A inhibitors or drugs known to prolong the QTc interval. (bula de Vepdegestranto, Advertências e precauções)

  • VilazodonaISRSGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • VortioxetinaantidepressivoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

  • ZiprasidonaantipsicóticoGrave

    …drugs, ziprasidone is contraindicated: • in patients with a known history of QT prolongation (including congenital long QT syndrome) • in patients with recent acute myocardial infarction • in patients with uncompensated heart failure Pharmacokinetic/pharmacodynamic studies between ziprasidone and other drugs that prolong the QT interval have not been performed. (bula de Ziprasidona, Contraindicações)

  • ZolmitriptanatriptanoGrave

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (bula de Escitalopram, Advertências e precauções)

Interações moderadas (189)

  • Acetazolamidainibidor da anidrase carbônicaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Ácido etacrínicodiurético de alçaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Ácido mefenâmicoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Amiloridadiurético poupador de potássioModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Anagrelidamedicamento que prolonga o intervalo QTModerada

    Monitor patients for bleeding, including those receiving concomitant therapy with other drugs known to cause bleeding (e.g., anticoagulants, PDE3 inhibitors, NSAIDs, antiplatelet agents, selective serotonin reuptake inhibitors) [see Drug Interactions (7.3) , Clinical Pharmacology (12.3) ] . (bula de Anagrelida, Advertências e precauções)

  • Anfepramona (dietilpropiona)estimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • ApixabanaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Arformoterolagonista beta-adrenérgicoModerada

    MAO inhibitors, tricyclic antidepressants and drugs that prolong the QTc interval may potentiate effect on the cardiovascular system. (bula de Arformoterol, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Armodafinilaestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Articaína + epinefrinaanestésico localModerada

    The administration of local anesthetic solutions containing epinephrine to patients receiving monoamine oxidase inhibitors, nonselective beta-adrenergic antagonists, or tricyclic antidepressants may produce severe, prolonged hypertension. (bula de Articaína + epinefrina, Interações medicamentosas)

  • Atenolol + clortalidonabetabloqueadorModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Benazepril + hidroclorotiazidainibidor da ECAModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Benzfetaminaestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • BivalirudinaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Caution is advised in patients taking tricyclic antidepressants which can affect the metabolism and uptake of circulating amines. (bula de Brimonidina, Interações medicamentosas)

  • Brimonidina + timololagonista alfa-adrenérgicoModerada

    CYP2D6 Inhibitors Potentiated systemic beta-blockade (e.g., decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g., quinidine, SSRIs) and timolol. (bula de Brimonidina + timolol, Interações medicamentosas)

  • Budesonida + formoterolcorticosteroideModerada

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (bula de Budesonida + formoterol, Interações medicamentosas)

  • Bumetanidadiurético de alçaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Bupivacaínaanestésico localModerada

    …Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants may… (bula de Bupivacaína, Advertências e precauções)

  • Bupivacaína + epinefrinaanestésico localModerada

    …Interactions with MARCAINE WITH EPINEPHRINE Risk of Severe, Persistent Hypertension Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving monoamine oxidase inhibitors (MAOI) or tricyclic antidepressants may… (bula de Bupivacaína + epinefrina, Advertências e precauções)

  • BupropionaantidepressivoModerada

    …hydrochloride extended-release tablets (XL), concurrent administration of bupropion hydrochloride extended-release tablets (XL) and agents that lower the seizure threshold (e.g., other bupropion products, antipsychotics, antidepressants, theophylline, or systemic corticosteroids) should be undertaken only with extreme caution [see Warnings and Precautions (5.3)] . (bula de Bupropiona, Interações medicamentosas)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Cangrelorantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Carbidopa + levodopa + entacaponamedicamento dopaminérgicoModerada

    • Tricyclic antidepressants: risk of hypertension and dyskinesia reported during concomitant use with carbidopa/levodopa ( 7.4 ) (bula de Carbidopa + levodopa + entacapona, Interações medicamentosas)

  • Carisoprodolrelaxante muscularModerada

    Since the sedative effects of carisoprodol and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) may be additive, appropriate caution should be exercised with patients who take more than one of these CNS depressants simultaneously. (bula de Carisoprodol, Advertências e precauções)

  • CelecoxibeAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • CetoprofenoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • CetorolacoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Cilostazolantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Cimetidinabloqueador H2Moderada

    …apparently through an effect on certain microsomal enzyme systems, has been reported to reduce the hepatic metabolism of warfarin-type anticoagulants, phenytoin, propranolol, nifedipine, chlordiazepoxide, diazepam, certain tricyclic antidepressants, lidocaine, theophylline, and metronidazole, thereby delaying elimination and increasing blood levels of these drugs. (bula de Cimetidina, Interações medicamentosas)

  • Cinacalceteinibidor da CYP2D6Moderada

    QT Interval Prolongation and V entricular A rr h ythmia Decreases in serum calcium can also prolong the QT interval, potentially resulting in ventricular arrhythmia. (bula de Cinacalcete, Advertências e precauções)

  • ClonazepambenzodiazepínicoModerada

    …Interactions The CNS-depressant action of the benzodiazepine class of drugs may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs. (bula de Clonazepam, Interações medicamentosas)

  • Clonidinaagonista alfa-adrenérgicoModerada

    Tricyclic antidepressants Clinical Implication Concomitant use of tricyclic antidepressants with clonidine can increase blood pressure and may counteract the hypotensive effects of clonidine. (bula de Clonidina, Interações medicamentosas)

  • Clopidogrelantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • ClorazepatobenzodiazepínicoModerada

    The actions of the benzodiazepines may be potentiated by barbiturates, narcotics, phenothiazines, monoamine oxidase inhibitors or other antidepressants. (bula de Clorazepato, Interações medicamentosas)

  • Cloroprocaínaanestésico localModerada

    Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (bula de Cloroprocaína, Precauções)

  • Clorotiazidadiurético tiazídicoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Clortalidonadiurético tiazídicoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • ClozapinaantipsicóticoModerada

    CYP2D6 and CYP3A4 Inhibitors Concomitant treatment with CLOZARIL and CYP2D6 or CYP3A4 inhibitors (e.g., cimetidine, escitalopram, erythromycin, paroxetine, bupropion, fluoxetine, quinidine, duloxetine, terbinafine, or sertraline) can increase clozapine levels and lead to adverse reactions [see Clinical Pharmacology ( 12.3 )] . (bula de Clozapina, Interações medicamentosas)

  • Cocaínaanestésico localModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • DabigatranaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Daridorexantosedativo-hipnóticoModerada

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression, which can cause daytime impairment. (bula de Daridorexanto, Advertências e precauções)

  • DarifenacinaanticolinérgicoModerada

    Caution should be taken when darifenacin extended-release tablets is used concomitantly with medications that are predominantly metabolized by CYP2D6 and which have a narrow therapeutic window, such as flecainide, thioridazine and tricyclic antidepressants ( 7.2 ) (bula de Darifenacina, Interações medicamentosas)

  • DarunavirantirretroviralModerada

    Antidepressants : Selective Serotonin Reuptake Inhibitors (SSRIs): paroxetine, sertraline ↓ paroxetine ↓ sertraline If either sertraline or paroxetine is initiated in patients receiving PREZISTA/ritonavir, dose titrating the SSRI based on a clinical assessment of antidepressant response is recommended. (bula de Darunavir, Interações medicamentosas)

  • Darunavir + cobicistateantirretroviralModerada

    Antidepressants: Selective Serotonin Reuptake Inhibitors (SSRIs): e.g. paroxetine, sertraline SSRIs: effects unknown When co-administering with SSRIs, TCAs, or trazodone, careful dose titration of the antidepressant to the desired effect, including using the lowest feasible initial or maintenance dose, and monitoring for antidepressant response are recommended. (bula de Darunavir + cobicistate, Interações medicamentosas)

  • Desfluranoanestésico geralModerada

    Carefully monitor cardiac rhythm when administering SUPRANE to susceptible patients (e.g., patients with congenital Long QT Syndrome or patients taking drugs that can prolong the QT interval). (bula de Desflurano, Advertências e precauções)

  • …that may Increase Risk of Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin… (bula de Desmopressina, Interações medicamentosas)

  • Dexmetilfenidatoestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • DiazepambenzodiazepínicoModerada

    …be given to the pharmacology of the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants. (bula de Diazepam, Interações medicamentosas)

  • DicicloverinaanticolinérgicoModerada

    …drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (bula de Dicicloverina, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • DiflunisalAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Dipiridamolantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Dorzolamida + timololinibidor da anidrase carbônicaModerada

    CYP2D6 Inhibitors Potentiated systemic beta-blockade (e.g., decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g., quinidine, SSRIs) and timolol. (bula de Dorzolamida + timolol, Interações medicamentosas)

  • DronabinolcanabinoideModerada

    Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect (e.g., barbiturates, benzodiazepines, lithium, opioids, buspirone, scopolamine, antihistamines, tricyclic antidepressants, other anticholinergic agents, and muscle relaxants). (bula de Dronabinol, Advertências e precauções)

  • Droperidolantagonista da dopaminaModerada

    …cardiac disease, 3) treatment with Class I and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval (see PRECAUTIONS, Drug Interactions ), and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs… (bula de Droperidol, Advertências)

  • EfavirenzantirretroviralModerada

    QT Prolonging Drugs There is limited information available on the potential for a pharmacodynamic interaction between efavirenz and drugs that prolong the QTc interval. (bula de Efavirenz, Interações medicamentosas)

  • Efavirenz + lamivudina + tenofovirantirretroviralModerada

    QT Prolonging Drugs There is limited information available on the potential for a pharmacodynamic interaction between EFV and drugs that prolong the QTc interval. (bula de Efavirenz + lamivudina + tenofovir, Interações medicamentosas)

  • Antidepressants: Selective Serotonin Reuptake Inhibitors (SSRIs) e.g., paroxetine Tricyclic Antidepressants (TCAs) e.g., amitriptyline desipramine imipramine nortriptyline bupropion trazodone ↑ SSRIs (except sertraline) ↑ TCAs ↑ trazodone Careful dosage titration of the antidepressant and monitoring for antidepressant response are recommended when coadministered… (bula de Elvitegravir + cobicistate + entricitabina + tenofovir, Interações medicamentosas)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • EnoxaparinaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Epinefrina (adrenalina)simpaticomiméticoModerada

    • Drugs that potentiate the effects of epinephrine include sympathomimetics, beta blockers, tricyclic antidepressants, MAO inhibitors, COMT inhibitors, clonidine, doxapram, oxytocin, levothyroxine sodium, and certain antihistamines. (bula de Epinefrina (adrenalina), Interações medicamentosas)

  • Eplerenonaantagonista da aldosteronaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Eptifibatidaantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Ergotamina + cafeínaalcaloide do ergotModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • EribulinaModerada

    QT Prolongation: Monitor for prolonged QT intervals in patients with congestive heart failure, bradyarrhythmias, drugs known to prolong the QT interval, and electrolyte abnormalities. (bula de Eribulina, Advertências e precauções)

  • EscopolaminaanticolinérgicoModerada

    Concomitant use of other drugs that cause central nervous system (CNS) adverse reactions (e.g., alcohol, sedatives, hypnotics, opiates, and anxiolytics) or have anticholinergic properties (e.g., other belladonna alkaloids, sedating antihistamines, meclizine, tricyclic antidepressants, and muscle relaxants) may increase this effect [see Drug Interactions ( 7.1 )] . (bula de Escopolamina, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Eszopiclonasedativo-hipnóticoModerada

    Additive effects occur with concomitant use of other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol), including daytime use. (bula de Eszopiclona, Advertências e precauções)

  • EtodolacoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Fendimetrazinaestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • FenilefrinadescongestionanteModerada

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (bula de Fenilefrina, Interações medicamentosas)

  • FenitoínaanticonvulsivanteModerada

    …Ethosuximide, felbamate, oxcarbazepine, methsuximide, topiramate Azoles Fluconazole, ketoconazole, itraconazole, miconazole, voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine,… (bula de Fenitoína, Interações medicamentosas)

  • FenoprofenoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Fenterminaestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Fentermina + topiramatoestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Fisostigminainibidor da colinesteraseModerada

    Acute cardiac arrest may be possible during treatment with tricyclic antidepressants; therefore, Anticholium should only be considered as an antidote for this indication while the patient has continuous ECG monitoring. (bula de Fisostigmina, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Fluticasona + salmeterolcorticosteroideModerada

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (bula de Fluticasona + salmeterol, Interações medicamentosas)

  • FondaparinuxanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Formoterolagonista beta-adrenérgicoModerada

    • MAO inhibitors, tricyclic antidepressants and drugs that prolong QTc interval may potentiate effect on the cardiovascular system. (bula de Formoterol, Interações medicamentosas)

  • FosamprenavirantirretroviralModerada

    Antidepressant: Paroxetine, trazodone ↓ Paroxetine Any paroxetine dose adjustment should be guided by clinical effect (tolerability and efficacy). ↑ Trazodone Adverse events of nausea, dizziness, hypotension, and syncope have been observed following coadministration of trazodone and ritonavir. (bula de Fosamprenavir, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteModerada

    …Ethosuximide, felbamate, oxcarbazepine, methsuximide, topiramate Azoles Fluconazole, ketoconazole, itraconazole, miconazole, voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine,… (bula de Fosfenitoína, Interações medicamentosas)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Furosemidadiurético de alçaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • GefitinibeModerada

    Increase IRESSA to 500 mg daily in patients receiving a strong CYP3A4 inducer (e.g., rifampicin, phenytoin, or tricyclic antidepressant) and resume IRESSA at 250 mg 7 days after discontinuation of the strong inducer [see Dosage and Administration (2.4) , Clinical Pharmacology (12.3) ] . (bula de Gefitinibe, Interações medicamentosas)

  • GlicopirrônioanticolinérgicoModerada

    Other Anticholinergic Drugs There is potential for an additive interaction between glycopyrrolate and concomitantly used anticholinergic drugs (e.g., tricyclic antidepressants, anti-epileptics, class I antiarrhythmics, anti­-spasmodics, amantadine) resulting in increased anticholinergic adverse reactions. (bula de Glicopirrônio, Interações medicamentosas)

  • GosserrelinaModerada

    Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (bula de Gosserrelina, Advertências e precauções)

  • HaloperidolantipsicóticoModerada

    Plasma concentrations of CYP2D6 substrates (e,g. tricyclic antidepressants such as desipramine or imipramine) may increase when they are co-administered with haloperidol. (bula de Haloperidol, Interações medicamentosas)

  • HeparinaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • IbuprofenoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Indapamidadiurético tiazídicoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • IndometacinaAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Ipratrópio + salbutamolanticolinérgicoModerada

    Monoamine Oxidase Inhibitors or Tricyclic Antidepressants Ipratropium Bromide and Albuterol Sulfate Inhalation Solution should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents because the action of albuterol sulfate on the cardiovascular… (bula de Ipratrópio + salbutamol, Interações medicamentosas)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Isofluranoanestésico geralModerada

    Monitor QT interval when administering FORANE to susceptible patients (e.g., patients with congenital Long QT Syndrome or patients taking drugs that can prolong the QT interval). (bula de Isoflurano, Advertências e precauções)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoModerada

    Drugs that may potentiate clinical response of Isoproterenol Clinical Impact The effects of isoproterenol may be potentiated by tricyclic antidepressants, monoamine oxidase inhibitors, levothyroxine sodium, and certain antihistamines, notably chlorpheniramine, tripelennamine, and diphenhydramine. (bula de Isoprenalina (isoproterenol), Interações medicamentosas)

  • Itraconazolantifúngico azólicoModerada

    SSRIs, Tricyclics and Related Antidepressants Venlafaxine Monitor for adverse reactions. (bula de Itraconazol, Interações medicamentosas)

  • Lapatinibeinibidor da glicoproteína PModerada

    TYKERB may prolong the QT interval in some patients. (bula de Lapatinibe, Advertências e precauções)

  • Lemborexantosedativo-hipnóticoModerada

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression, which can cause daytime impairment. (bula de Lemborexanto, Advertências e precauções)

  • Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (bula de Leuprorrelina, Advertências e precauções)

  • Levossalbutamolagonista beta-adrenérgicoModerada

    Monoamine oxidase inhibitors (MAOs) or tricyclic antidepressants : May potentiate effect of albuterol on the cardiovascular system. (bula de Levossalbutamol, Interações medicamentosas)

  • Levotiroxinahormônio tireoidianoModerada

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (bula de Levotiroxina, Interações medicamentosas)

  • Lidocaínaanestésico localModerada

    Clinically Significant Drug Interactions The administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors or tricyclic antidepressants may produce severe, prolonged hypertension. (bula de Lidocaína, Interações medicamentosas)

  • Lidocaína + epinefrinaanestésico localModerada

    …Adverse Reactions Due to Drug Interactions with FLAVALTA Risk of Severe, Persistent Hypertension Due to Drug Interactions Between FLAVALTA and Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Administration of FLAVALTA (containing a vasoconstrictor, epinephrine) in patients receiving monoamine oxidase inhibitors (MAOI), or tricyclic antidepressants may result… (bula de Lidocaína + epinefrina, Advertências e precauções)

  • Liotironinahormônio tireoidianoModerada

    Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and liothyronine sodium may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (bula de Liotironina, Interações medicamentosas)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Risk of QT Prolongation : Lofexidine tablets prolong the QT interval. (bula de Lofexidina, Advertências e precauções)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • LumateperonaantipsicóticoModerada

    Monitor all antidepressant-treated patients, especially during the initial few months of anti-depressant drug therapy, and at times of dosage changes. (bula de Lumateperona, Advertências e precauções)

  • LurasidonaantipsicóticoModerada

    Activation of Mania/Hypomania Antidepressant treatment can increase the risk of developing a manic or hypomanic episode, particularly in patients with bipolar disorder. (bula de Lurasidona, Advertências e precauções)

  • MefloquinaantimaláricoModerada

    Other Drugs that Prolong the QTc Interval Coadministration of other drugs known to alter cardiac conduction (e.g., anti-arrhythmic or beta-adrenergic blocking agents, calcium channel blockers, antihistamines or H 1 -blocking agents, tricyclic antidepressants and phenothiazines) might also contribute to a prolongation of the QTc interval. (bula de Mefloquina, Interações medicamentosas)

  • MeloxicamAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Mepivacaínaanestésico localModerada

    Likewise, solutions of mepivacaine containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (bula de Mepivacaína, Advertências)

  • MetilescopolaminaanticolinérgicoModerada

    Drug interactions Additive anticholinergic effects may result from concomitant use with antipsychotics, tricyclic antidepressants, and other drugs with anticholinergic effects. (bula de Metilescopolamina, Interações medicamentosas)

  • Metilfenidatoestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • Metolazonadiurético tiazídicoModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • MetronidazolantibióticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Mifepristonainibidor da CYP3A4Moderada

    There is little or no experience with high exposure, concomitant dosing with other QT-prolonging drugs, or potassium channel variants resulting in a long QT interval. [See Warnings & Precautions ( 5.6 )] To minimize risk, the lowest effective dose should always be used. (bula de Mifepristona, Advertências e precauções)

  • Modafinilaestimulante do SNCModerada

    The risk is increased with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, meperidine, methadone, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. (bula de Escitalopram, Advertências e precauções)

  • MoxifloxacinofluoroquinolonaModerada

    Pharmacokinetic studies between moxifloxacin and other drugs that prolong the QT interval such as cisapride, erythromycin, antipsychotics, and tricyclic antidepressants have not been performed. (bula de Moxifloxacino, Advertências e precauções)

  • NabumetonaAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • NalbufinaopioideModerada

    Serotonergic Drugs The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), triptans, 5-HT3 receptor antagonists, drugs that effect the serotonin neurotransmitter system… (bula de Nalbufina, Interações medicamentosas)

  • Naltrexona + bupropionaantagonista opioideModerada

    Drugs Metabolized by CYP2D6: Bupropion inhibits CYP2D6 and can increase concentrations of antidepressants, (e.g., selective serotonin reuptake inhibitors and many tricyclics), antipsychotics (e.g., haloperidol, risperidone and thioridazine), beta-blockers (e.g., metoprolol) and Type 1C antiarrhythmics (e.g., propafenone and flecainide). (bula de Naltrexona + bupropiona, Interações medicamentosas)

  • NaproxenoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Nirmatrelvir + ritonavirantiviralModerada

    Antidepressants bupropion ↓ bupropion and active metabolite hydroxy-bupropion Monitor for an adequate clinical response to bupropion. trazodone ↑ trazodone Adverse reactions of nausea, dizziness, hypotension, and syncope have been observed following co-administration of trazodone and ritonavir. (bula de Nirmatrelvir + ritonavir, Interações medicamentosas)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • OxaprozinaAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Oxibato de sódiodepressor do SNCModerada

    The concurrent use of Xyrem with other CNS depressants, including but not limited to opioid analgesics, benzodiazepines, sedating antidepressants or antipsychotics, sedating anti-epileptic drugs, general anesthetics, muscle relaxants, and/or illicit CNS depressants, may increase the risk of respiratory depression, hypotension, profound sedation, syncope, and… (bula de Oxibato de sódio, Advertências e precauções)

  • PaliperidonaantipsicóticoModerada

    …combination with other drugs that are known to prolong QTc including Class 1A (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications, antipsychotic medications (e.g., chlorpromazine, thioridazine), antibiotics (e.g., gatifloxacin, moxifloxacin), or any other class of medications known to prolong the QTc interval. (bula de Paliperidona, Advertências e precauções)

  • Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • PasireotidaModerada

    Drugs that Prolong QT: Use with caution in patients who are at significant risk of developing QTc prolongation. (bula de Pasireotida, Interações medicamentosas)

  • PiroxicamAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • PonesimodeimunossupressorModerada

    Anti-Arrhythmic Drugs, QT Prolonging Drugs, Drugs that may Decrease Heart Rate PONVORY has not been studied in patients taking QT prolonging drugs. (bula de Ponesimode, Interações medicamentosas)

  • Prasugrelantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Prilocaína + epinefrinaanestésico localModerada

    …Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension. (bula de Prilocaína + epinefrina, Interações medicamentosas)

  • PrimaquinaantimaláricoModerada

    QT Interval Prolonging Drugs The pharmacodynamic interaction potential to prolong the QT interval of the electrocardiogram between Primaquine phosphate Tablets and other drugs that effect cardiac conduction is unknown. (bula de Primaquina, Interações medicamentosas)

  • QuetiapinaantipsicóticoModerada

    It is generally believed (though not established in controlled trials) that treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/manic episode in patients at risk for bipolar disorder. (bula de Quetiapina, Advertências e precauções)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Ranolazinamedicamento que prolonga o intervalo QTModerada

    Drugs transported by P-gp (e.g., digoxin), or drugs metabolized by CYP2D6 (e.g., tricyclic antidepressants) may need reduced doses when used with ASPRUZYO Sprinkle. (bula de Ranolazina, Interações medicamentosas)

  • RifampicinaantibióticoModerada

    …5-HT 3 Receptor Antagonists Ondansetron Decrease exposure Statins Metabolized by CYP3A4 Simvastatin Decrease exposure Thiazolidinediones Rosiglitazone Decrease AUC by 66% Tricyclic Antidepressants Nortriptyline A tuberculosis treatment regimen including rifampin (600 mg/day), isoniazid (300 mg/day), pyrazinamide (500 mg 3× per day), and pyridoxine (25 mg) was… (bula de Rifampicina, Interações medicamentosas)

  • RifapentinaantibióticoModerada

    …levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines Theophylline Narcotic analgesics Methadone Phosphodiesterase-5 (PDE-5) Inhibitors Sildenafil Thyroid preparations Levothyroxine Tricyclic antidepressants Amitriptyline, nortriptyline 7.5 Other Interactions The conversion of PRIFTIN to 25-desacetyl rifapentine is mediated by an esterase enzyme. (bula de Rifapentina, Interações medicamentosas)

  • RilpivirinaantirretroviralModerada

    In healthy subjects, 75 mg once daily and 300 mg once daily (3 times and 12 times the dose in EDURANT) have been shown to prolong the QTc interval of the electrocardiogram. (bula de Rilpivirina, Advertências e precauções)

  • RitonavirantirretroviralModerada

    Antidepressants: nefazodone, selective serotonin reuptake inhibitors (SSRIs): e.g. fluoxetine, paroxetine, tricyclics: e.g. amitriptyline, nortriptyline ↑ antidepressants A dose decrease may be needed for these drugs when co-administered with ritonavir. (bula de Ritonavir, Interações medicamentosas)

  • RivaroxabanaanticoagulanteModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Rocurôniobloqueador neuromuscularModerada

    QT Interval Prolongation The overall analysis of ECG data in pediatric patients indicates that the concomitant use of Rocuronium Bromide Injection with general anesthetic agents can prolong the QTc interval [see Clinical Studies ( 14.3 )]. (bula de Rocurônio, Advertências e precauções)

  • Salbutamolagonista beta-adrenérgicoModerada

    Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (bula de Salbutamol, Interações medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (bula de Salmeterol, Interações medicamentosas)

  • SalsalatoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Sevofluranoanestésico geralModerada

    Caution should be exercised when administering sevoflurane to susceptible patients (e.g., patients with congenital Long QT Syndrome or patients taking drugs that can prolong the QT interval). (bula de Sevoflurano, Advertências)

  • SorafenibeModerada

    Monitor electrolytes and electrocardiograms in patients with congestive heart failure, bradyarrhythmias, drugs known to prolong the QT interval, including Class Ia and III antiarrhythmics. (bula de Sorafenibe, Advertências e precauções)

  • SotalolbetabloqueadorModerada

    Additive to other QT-prolonging drugs ( 7.1 , 7.2 ) (bula de Sotalol, Interações medicamentosas)

  • Drugs that Prolong the QT interval QT prolongation has been reported with metronidazole, a component of bismuth subcitrate potassium, metronidazole and tetracycline hydrochloride, particularly when administered with drugs with the potential for prolonging the QT interval. (bula de Subcitrato de bismuto + metronidazol + tetraciclina, Advertências e precauções)

  • The efficacy of tricyclic antidepressants can decrease when coadministered with sulfamethoxazole and trimethoprim. (bula de Sulfametoxazol + trimetoprima, Interações medicamentosas)

  • SulindacoAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • SunitinibeModerada

    Drugs that Prolong QT Interval SUTENT is associated with QTc interval prolongation [see Warnings and Precautions (5.3) , Clinical Pharmacology (12.2) ] . (bula de Sunitinibe, Interações medicamentosas)

  • Suvorexantosedativo-hipnóticoModerada

    Co-administration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression. (bula de Suvorexanto, Advertências e precauções)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • TemazepambenzodiazepínicoModerada

    The benzodiazepines, including temazepam, produce additive CNS-depressant effects when co-administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics. (bula de Temazepam, Interações medicamentosas)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Terbutaline sulfate should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of terbutaline sulfate on the vascular system may be potentiated. (bula de Terbutalina, Precauções)

  • Ticagrelorantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Tirofibanaantiagregante plaquetárioModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Tizanidinarelaxante muscularModerada

    The CNS depressant effects of Zanaflex with alcohol and other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants) may be additive [see Drug Interactions ( 7.4 )] . (bula de Tizanidina, Advertências e precauções)

  • TolmetinaAINEModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Toremifenomodulador seletivo do receptor de estrogênioModerada

    …quinidine, procainamide, disopyramide) and Class III (e.g., amiodarone, sotalol, ibutilide, dofetilide) antiarrhythmics; certain antipsychotics (e.g., thioridazine, haloperidol); certain antidepressants (e.g., venlafaxine, amitriptyline); certain antibiotics (e.g., erythromycin, clarithromycin, levofloxacin, ofloxacin); and certain anti-emetics (e.g., ondansetron, granisetron). (bula de Toremifeno, Interações medicamentosas)

  • Trianterenodiurético poupador de potássioModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (bula de Triptorrelina, Advertências e precauções)

  • Umeclidínio + vilanterolanticolinérgicoModerada

    • Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution. (bula de Umeclidínio + vilanterol, Interações medicamentosas)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • VarfarinaanticoagulanteModerada

    For patients taking warfarin, carefully monitor the international normalized ratio [see Drug Interactions ( 7 )] . (bula de Escitalopram, Advertências e precauções)

  • VasopressinaModerada

    Drugs Suspected of Causing SIADH Use with drugs suspected of causing SIADH (e.g., SSRIs, tricyclic antidepressants, haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate) may increase the pressor effect in addition to the antidiuretic effect of Vasostrict ® . (bula de Vasopressina, Interações medicamentosas)

  • Zaleplonasedativo-hipnóticoModerada

    Coadministration with other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol) increases the risk of CNS depression. (bula de Zaleplona, Advertências)

  • Zolpidemsedativo-hipnóticoModerada

    Additive effects occur with concomitant use of other CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants, alcohol), including daytime use [see Drug Interactions (7.1) ] . (bula de Zolpidem, Advertências e precauções)

Menções leves (38)

  • Ácido valproicoanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • AtazanavirantirretroviralLeve

    Antidepressants: tricyclic antidepressants ↑ tricyclic antidepressants Coadministration with REYATAZ has the potential to produce serious and/or life-threatening adverse events and has not been studied. (bula de Atazanavir, Interações medicamentosas)

  • BenzatropinaanticolinérgicoLeve

    Paralytic ileus, hyperthermia and heat stroke, all of which have sometimes been fatal, have occurred in patients taking anticholinergic-type antiparkinsonism drugs, including benztropine mesylate, in combination with phenothiazines and/or tricyclic antidepressants. (bula de Benzatropina, Advertências)

  • BrexpiprazolantipsicóticoLeve

    However, there is substantial evidence from placebo-controlled maintenance studies in adults with MDD that antidepressants delay the recurrence of depression. (bula de Brexpiprazol, Advertências e precauções)

  • BrivaracetamanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • There have been rare reports of adverse reactions, including hypertension and dyskinesia, resulting from the concomitant use of tricyclic antidepressants and carbidopa-levodopa preparations. (bula de Carbidopa, Interações medicamentosas)

  • CariprazinaantipsicóticoLeve

    …placebo-controlled trials of adult patients with major depressive disorder, the proportion of patients with shifts in fasting glucose from normal (<100 mg/dL) to high (≥126 mg/dL) was greatest in the VRAYLAR 3 mg per day + antidepressant therapy arm (3.2%) compared with those taking VRAYLAR 1.5 mg per day + antidepressant therapy (2%) or those placebo-treated (1.3%). (bula de Cariprazina, Advertências e precauções)

  • CenobamatoanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • ClobazambenzodiazepínicoLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • EluxadolinaopioideLeve

    Mechanism and Clinical Effect(s) Concomitant use of Escitalopram Capsules and other serotonergic drugs (including other SSRIs, SNRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St. (bula de Escitalopram, Interações medicamentosas)

  • EslicarbazepinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • EtossuximidaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • FelbamatoanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • GabapentinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • Hidroxizinaanti-histamínicoLeve

    …quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmics, certain antipsychotics (e.g., ziprasidone, iloperidone, clozapine, quetiapine, chlorpromazine), certain antidepressants (e.g., citalopram, fluoxetine), certain antibiotics (e.g., azithromycin, erythromycin, clarithromycin, gatifloxacin, moxifloxacin); and others (e.g., pentamidine, methadone,… (bula de Hidroxizina, Precauções)

  • LacosamidaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • LamotriginaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • LevetiracetamanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • LovastatinaestatinaLeve

    These include itraconazole, ketoconazole, posaconazole, voriconazole, the macrolide antibiotics erythromycin and clarithromycin, the ketolide antibiotic telithromycin, HIV protease inhibitors, boceprevir, telaprevir, the antidepressant nefazodone, or cobicistat-containing products. (bula de Lovastatina, Advertências)

  • Mesuximida (metossuximida)anticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • OxcarbazepinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • Mechanism and Clinical Effect(s) Concomitant use of Escitalopram Capsules and other serotonergic drugs (including other SSRIs, SNRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St. (bula de Escitalopram, Interações medicamentosas)

  • PerampanelanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • PerfenazinaantipsicóticoLeve

    Drug Interactions Metabolism of a number of medications, including antipsychotics, antidepressants, β-blockers, and antiarrhythmics, occurs through the cytochrome P450 2D6 isoenzyme (debrisoquine hydroxylase). (bula de Perfenazina, Interações medicamentosas)

  • PregabalinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • PrimidonaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • PropranololbetabloqueadorLeve

    Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers. (bula de Propranolol, Interações medicamentosas)

  • QuinidinaantiarrítmicoLeve

    Cytochrome P450 IID6 is an enzyme critical to the metabolism of many drugs, notably including mexiletine , some phenothiazines , and most polycyclic antidepressants . (bula de Quinidina, Interações medicamentosas)

  • RufinamidaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • TerbinafinaantifúngicoLeve

    Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (bula de Terbinafina, Interações medicamentosas)

  • TiagabinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • It is difficult to determine if Tolcapone tablets played a role in the pathogenesis of these events because these patients received several concomitant medications affecting the central nervous system such as monoaminergic (i.e., MAO-I, tricyclic and selective serotonin reuptake inhibitors) and anticholinergic agents. (bula de Tolcapona, Precauções)

  • TopiramatoanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • TriexifenidilanticolinérgicoLeve

    Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. (bula de Triexifenidil, Interações medicamentosas)

  • VigabatrinaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

  • ZonisamidaanticonvulsivanteLeve

    Seizures Although anticonvulsant effects of racemic citalopram have been observed in animal studies, Escitalopram Capsules have not been systematically evaluated in patients with a seizure disorder. (bula de Escitalopram, Advertências e precauções)

Nenhuma interação significativa relatada (3)

  • Desloratadinaanti-histamínicoSem interação

    …changes in the safety profile of desloratadine. [See Clinical Pharmacology (12.3) .] 7.2 Fluoxetine In controlled clinical studies co-administration of desloratadine with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), resulted in increased plasma concentrations of desloratadine and 3 hydroxydesloratadine, but there were no clinically relevant changes… (bula de Desloratadina, Interações medicamentosas)

  • EntacaponaSem interação

    No interaction with the tricyclic antidepressant imipramine was shown in a single-dose study with entacapone without coadministered levodopa and dopa-decarboxylase inhibitor. (bula de Entacapona, Precauções)

  • Ropinirolagonista da dopaminaSem interação

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (bula de Ropinirol, Interações medicamentosas)

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