تداخلات حمض البيمبيدويك

Intervention : Avoid concomitant use of NEXLETOL with simvastatin greater than 20 mg. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Intervention: Avoid concomitant use of NEXLETOL with pravastatin greater than 40 mg. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Intervention : Avoid concomitant use of NEXLETOL with simvastatin greater than 20 mg. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Table 3: Drug Interactions that may Decrease Exposure to LIPITOR Rifampin Clinical Impact: Concomitant administration of LIPITOR with rifampin, an inducer of cytochrome P450 3A4 and inhibitor of OATP1B1, can lead to variable reductions in plasma concentrations of atorvastatin. (نشرة أتورفاستاتين، التداخلات الدوائية)

Drug Interactions that may Decrease Exposure to Atorvastatin Rifampin Clinical Impact: Concomitant administration of atorvastatin with rifampin, an inducer of cytochrome P450 3A4 and inhibitor of OATP1B1, can lead to variable reductions in plasma concentrations of atorvastatin. (نشرة أملوديبين وأتورفاستاتين، التداخلات الدوائية)

Table 2: Established and Other Potentially Clinically Relevant Interactions Affecting VIBERZI OATP1B1 Inhibitors Clinical Impact: Increased exposure to eluxadoline when coadministered with cyclosporine [ see Clinical Pharmacology ( 12.3 ) ] Intervention: Administer VIBERZI at a dose of 75 mg twice daily [see Dosage and Administration ( 2 )] and monitor patients… (نشرة إيلوكسادولين، التداخلات الدوائية)

Fibrates Clinical Impact: Concomitant administration of fibrates with NEXLETOL resulted in increased triglycerides and decreased high-density lipoprotein cholesterol (HDL-C) in some patients in clinical studies and post-marketing reports. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Fibrates Clinical Impact: Concomitant administration of fibrates with NEXLETOL resulted in increased triglycerides and decreased high-density lipoprotein cholesterol (HDL-C) in some patients in clinical studies and post-marketing reports. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Fibrates Clinical Impact: Concomitant administration of fibrates with NEXLETOL resulted in increased triglycerides and decreased high-density lipoprotein cholesterol (HDL-C) in some patients in clinical studies and post-marketing reports. (نشرة حمض البيمبيدويك، التداخلات الدوائية)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

The pharmacokinetics of maraviroc are likely to be modulated by inhibitors and inducers of CYP3A and P-gp and may be modulated by inhibitors of OATP1B1 and MRP2. (نشرة مارافيروك، التداخلات الدوائية)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)

Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (نشرة حمض البيمبيدويك، التحذيرات والاحتياطات)