Diazotan izosorbidu: interakcje

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (etykieta leku Nitrogliceryna, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking the soluble guanylate cyclase stimulator riociguat. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (etykieta leku Diazotan izosorbidu, Przeciwwskazania)

Hypotension Adenosine injection is a potent peripheral vasodilator and can induce significant hypotension. (etykieta leku Adenozyna, Ostrzeżenia i środki ostrożności)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etykieta leku Alfuzosyna, Ostrzeżenia i środki ostrożności)

Alcohol, in particular, has been found to exhibit additive effects of this variety. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Nonetheless, caution, as with any other peripheral vasodilator, should be exercised when administering amlodipine, particularly in patients with severe aortic stenosis. (etykieta leku Amlodypina + walsartan, Ostrzeżenia i środki ostrożności)

Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics… (etykieta leku Artykaina + adrenalina, Interakcje z innymi lekami)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (etykieta leku Bupiwakaina, Interakcje z innymi lekami)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (etykieta leku Bupiwakaina + adrenalina, Interakcje z innymi lekami)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (etykieta leku Chloroprokaina, Środki ostrożności)

• Co-administration with Other Vasodilators or Negative Chronotropic Agents : Use with caution due to additive pharmacodynamic effects. (etykieta leku Deksmedetomidyna, Ostrzeżenia i środki ostrożności)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

…drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (etykieta leku Dicykloweryna, Interakcje z innymi lekami)

…oral anticoagulants, calcium channel blockers, beta blockers, cardiac glycosides, inducers of CYP3A4, substrates and inhibitors of CYP3A4, substrates and inhibitors of P-glycoprotein, nitrates, sulphonylureas, loop diuretics, potassium sparing diuretics, thiazide diuretics, substrates and inhibitors of tubular organic cation transport, and QTc-prolonging drugs. (etykieta leku Dofetylid, Interakcje z innymi lekami)

Most cases reported product application with use under occlusion, genital application, or application to a large body surface area which may increase the systemic absorption of econazole nitrate. (etykieta leku Ekonazol, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Co-administration of vaginal miconazole nitrate and Etonogestrel/Ethinyl Estradiol Vaginal Ring increases the serum concentrations of etonogestrel and ethinyl estradiol by up to 40% [see Clinical Pharmacology (12.3) ] . (etykieta leku Etonogestrel + etynyloestradiol, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Valvular Stenosis There is concern, on theoretical grounds, that patients with aortic stenosis might be at particular risk of decreased coronary perfusion when treated with vasodilators because they do not develop as much afterload reduction as others. (etykieta leku Kaptopryl, Środki ostrożności)

Drugs Associated with Methemoglobinemia: Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (etykieta leku Lidokaina + adrenalina, Interakcje z innymi lekami)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (etykieta leku Lidokaina + prylokaina, Interakcje z innymi lekami)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitroglycerin, nitroprusside, nitric oxide, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (etykieta leku Mepiwakaina, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Caution should also be used when niacin extended-release tablets are used in patients with unstable angina or in the acute phase of an MI, particularly when such patients are also receiving vasoactive drugs such as nitrates, calcium channel blockers, or adrenergic blocking agents. (etykieta leku Niacyna (kwas nikotynowy), Ostrzeżenia i środki ostrożności)

Nifedipine is a vasodilator, and co-administration of other drugs affecting blood pressure may result in pharmacodynamic interactions. (etykieta leku Nifedypina, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: EXAMPLES OF DRUGS ASSOCIATED WITH METHEMOGLOBINEMIA: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (etykieta leku Prylokaina + adrenalina, Interakcje z innymi lekami)

…exposed to the following drugs, which could include other local anesthetics [see Warnings and Precautions ( 5.4 )] : Examples of Drugs Associated with Methemoglobinemia Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (etykieta leku Ropiwakaina, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Antihypertensive Agents Verapamil administered concomitantly with oral antihypertensive agents (e.g., vasodilators, angiotensin-converting enzyme inhibitors, diuretics, beta blockers) will usually have an additive effect on lowering blood pressure. (etykieta leku Werapamil, Interakcje z innymi lekami)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (etykieta leku Diazotan izosorbidu, Interakcje z innymi lekami)

Drugs antagonizing pressor effects of epinephrine α-blockers, such as phentolamine Vasodilators, such as nitrates Diuretics Antihypertensives Ergot alkaloids Drugs potentiating pressor effects of epinephrine • Sympathomimetics • β-blockers, such as propranolol • Tricyclic anti-depressants • Monoamine oxidase (MAO) inhibitors • Catechol-O-methyl transferase (COMT)… (etykieta leku Adrenalina, Interakcje z innymi lekami)

Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (etykieta leku Dobutamina, Interakcje z innymi lekami)

Alpha-adrenergic antagonists and PDE-5 inhibitors are both vasodilators that can lower blood pressure. (etykieta leku Dutasteryd + tamsulosyna, Ostrzeżenia i środki ostrożności)

Other Cardiovascular Agents Enalapril has been used concomitantly with beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (etykieta leku Enalapryl + hydrochlorotiazyd, Interakcje z innymi lekami)

Other Cardiovascular Agents Enalaprilat injection, USP has been used concomitantly with digitalis, beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (etykieta leku Enalaprylat, Interakcje z innymi lekami)

…acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically… (etykieta leku Finasteryd, Interakcje z innymi lekami)

Other Agents: Lisinopril has been used concomitantly with nitrates and/or digoxin without evidence of clinically significant adverse interactions. (etykieta leku Lizynopryl + hydrochlorotiazyd, Interakcje z innymi lekami)

Post injury arterial injection of vasodilators and/or arterial infusion of parenteral fluids are generally regarded to be of no value in altering outcome. (etykieta leku Metoheksital, Ostrzeżenia)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (etykieta leku Sylodosyna, Ostrzeżenia i środki ostrożności)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (etykieta leku Tamsulosyna, Ostrzeżenia i środki ostrożności)

Drug Interactions with Amlodipine In clinical trials, amlodipine has been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. (etykieta leku Telmisartan + amlodypina, Interakcje z innymi lekami)