Interações de Dinitrato de isossorbida

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (bula de Nitroglicerina, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking the soluble guanylate cyclase stimulator riociguat. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Do not use Isosorbide Dinitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil. (bula de Dinitrato de isossorbida, Contraindicações)

Hypotension Adenosine injection is a potent peripheral vasodilator and can induce significant hypotension. (bula de Adenosina, Advertências e precauções)

Alcohol, in particular, has been found to exhibit additive effects of this variety. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (bula de Alfuzosina, Advertências e precauções)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Nonetheless, caution, as with any other peripheral vasodilator, should be exercised when administering amlodipine, particularly in patients with severe aortic stenosis. (bula de Anlodipino + valsartana, Advertências e precauções)

Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics… (bula de Articaína + epinefrina, Interações medicamentosas)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (bula de Bupivacaína, Interações medicamentosas)

• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (bula de Bupivacaína + epinefrina, Interações medicamentosas)

Valvular Stenosis There is concern, on theoretical grounds, that patients with aortic stenosis might be at particular risk of decreased coronary perfusion when treated with vasodilators because they do not develop as much afterload reduction as others. (bula de Captopril, Precauções)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (bula de Cloroprocaína, Precauções)

• Co-administration with Other Vasodilators or Negative Chronotropic Agents : Use with caution due to additive pharmacodynamic effects. (bula de Dexmedetomidina, Advertências e precauções)

…drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (bula de Dicicloverina, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

…oral anticoagulants, calcium channel blockers, beta blockers, cardiac glycosides, inducers of CYP3A4, substrates and inhibitors of CYP3A4, substrates and inhibitors of P-glycoprotein, nitrates, sulphonylureas, loop diuretics, potassium sparing diuretics, thiazide diuretics, substrates and inhibitors of tubular organic cation transport, and QTc-prolonging drugs. (bula de Dofetilida, Interações medicamentosas)

Most cases reported product application with use under occlusion, genital application, or application to a large body surface area which may increase the systemic absorption of econazole nitrate. (bula de Econazol, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Co-administration of vaginal miconazole nitrate and Etonogestrel/Ethinyl Estradiol Vaginal Ring increases the serum concentrations of etonogestrel and ethinyl estradiol by up to 40% [see Clinical Pharmacology (12.3) ] . (bula de Etonogestrel + etinilestradiol, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Drugs Associated with Methemoglobinemia: Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (bula de Lidocaína + epinefrina, Interações medicamentosas)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (bula de Lidocaína + prilocaína, Interações medicamentosas)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitroglycerin, nitroprusside, nitric oxide, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (bula de Mepivacaína, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Caution should also be used when niacin extended-release tablets are used in patients with unstable angina or in the acute phase of an MI, particularly when such patients are also receiving vasoactive drugs such as nitrates, calcium channel blockers, or adrenergic blocking agents. (bula de Niacina (ácido nicotínico), Advertências e precauções)

Nifedipine is a vasodilator, and co-administration of other drugs affecting blood pressure may result in pharmacodynamic interactions. (bula de Nifedipino, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

…methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: EXAMPLES OF DRUGS ASSOCIATED WITH METHEMOGLOBINEMIA: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (bula de Prilocaína + epinefrina, Interações medicamentosas)

…exposed to the following drugs, which could include other local anesthetics [see Warnings and Precautions ( 5.4 )] : Examples of Drugs Associated with Methemoglobinemia Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine,… (bula de Ropivacaína, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Antihypertensive Agents Verapamil administered concomitantly with oral antihypertensive agents (e.g., vasodilators, angiotensin-converting enzyme inhibitors, diuretics, beta blockers) will usually have an additive effect on lowering blood pressure. (bula de Verapamil, Interações medicamentosas)

Drug Interactions The vasodilating effects of isosorbide dinitrate may be additive with those of other vasodilators. (bula de Dinitrato de isossorbida, Interações medicamentosas)

Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (bula de Dobutamina, Interações medicamentosas)

Alpha-adrenergic antagonists and PDE-5 inhibitors are both vasodilators that can lower blood pressure. (bula de Dutasterida + tansulosina, Advertências e precauções)

Other Cardiovascular Agents Enalapril has been used concomitantly with beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (bula de Enalapril + hidroclorotiazida, Interações medicamentosas)

Other Cardiovascular Agents Enalaprilat injection, USP has been used concomitantly with digitalis, beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions. (bula de Enalaprilate, Interações medicamentosas)

Drugs antagonizing pressor effects of epinephrine α-blockers, such as phentolamine Vasodilators, such as nitrates Diuretics Antihypertensives Ergot alkaloids Drugs potentiating pressor effects of epinephrine • Sympathomimetics • β-blockers, such as propranolol • Tricyclic anti-depressants • Monoamine oxidase (MAO) inhibitors • Catechol-O-methyl transferase (COMT)… (bula de Epinefrina (adrenalina), Interações medicamentosas)

…acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically… (bula de Finasterida, Interações medicamentosas)

Other Agents: Lisinopril has been used concomitantly with nitrates and/or digoxin without evidence of clinically significant adverse interactions. (bula de Lisinopril + hidroclorotiazida, Interações medicamentosas)

Post injury arterial injection of vasodilators and/or arterial infusion of parenteral fluids are generally regarded to be of no value in altering outcome. (bula de Metoexital, Advertências)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (bula de Silodosina, Advertências e precauções)

Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (bula de Tansulosina, Advertências e precauções)

Drug Interactions with Amlodipine In clinical trials, amlodipine has been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. (bula de Telmisartana + anlodipino, Interações medicamentosas)