Interacciones de Bicalutamida

These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (etiqueta de Doravirina, Contraindicaciones)

Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (etiqueta de Finasterida, Contraindicaciones)

CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (etiqueta de Gonadotropina coriónica, Contraindicaciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (etiqueta de Coriogonadotropina alfa, Precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (etiqueta de Estradiol y noretisterona, Advertencias y precauciones)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (etiqueta de Estrógenos conjugados, Precauciones)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (etiqueta de Estrógenos conjugados y bazedoxifeno, Advertencias y precauciones)

Some patients had serious bleeding including intracranial, retroperitoneal, and gastrointestinal requiring blood transfusion and/or administration of vitamin K. (etiqueta de Bicalutamida, Advertencias y precauciones)

Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (etiqueta de Fludrocortisona, Interacciones medicamentosas)

For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (etiqueta de Folitropina, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

…medications, pramlintide acetate, insulin, angiotensin converting enzyme (ACE) inhibitors, H 2 receptor antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs… (etiqueta de Glimepirida, Interacciones medicamentosas)

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (etiqueta de Goserelina, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (etiqueta de Leuprorelina, Advertencias y precauciones)

Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)

Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (etiqueta de Liotironina, Interacciones medicamentosas)

Weak CYP3A4 Inhibitors Weak CYP3A4 inhibitors (such as alprazolam, amiodarone, amlodipine, atorvastatin, bicalutamide, cilostazol, cimetidine, cyclosporine, fluoxetine, fluvoxamine, ginkgo, goldenseal, isoniazid, lapatinib, nilotinib, pazopanib, ranitidine, ranolazine, ticagrelor, zileuton) can increase lomitapide exposure approximately 2-fold [see Clinical Pharmacology… (etiqueta de Lomitapida, Interacciones medicamentosas)

However, clinical studies have shown that lovastatin does not reduce basal plasma cortisol concentration or impair adrenal reserve, and does not reduce basal plasma testosterone concentration. (etiqueta de Lovastatina, Interacciones medicamentosas)

The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (etiqueta de Medroxiprogesterona, Interacciones medicamentosas)

Clinical studies have shown that with co-administration of bicalutamide, mean midazolam (a CYP 3A4 substrate) levels may be increased 1.5-fold (for C max ) and 1.9-fold (for AUC). (etiqueta de Bicalutamida, Interacciones medicamentosas)

…anti-diabetic medications, pramlintide acetate, insulin, angiotensin converting enzyme (ACE) inhibitors, H2 receptor antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs… (etiqueta de Pioglitazona y glimepirida, Interacciones medicamentosas)

Reproductive effects: Include decreased testosterone and increased prolactin levels. (etiqueta de Ramelteón, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)

Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (etiqueta de Tamoxifeno, Advertencias y precauciones)

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (etiqueta de Triptorelina, Advertencias y precauciones)

Some patients had serious bleeding including intracranial, retroperitoneal, and gastrointestinal requiring blood transfusion and/or administration of vitamin K. (etiqueta de Bicalutamida, Advertencias y precauciones)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (etiqueta de Bicalutamida, Advertencias y precauciones)