बाइकैलुटामाइड के इंटरैक्शन

CONTRAINDICATIONS: Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to HCG. (कोरियोनिक गोनाडोट्रोपिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

These drugs include, but are not limited to, the following: the anticonvulsants carbamazepine, oxcarbazepine, phenobarbital, phenytoin the androgen receptor inhibitor enzalutamide the antimycobacterials rifampin, rifapentine the cytotoxic agent mitotane St. (डोराविरिन लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Because of the ability of Type II 5α-reductase inhibitors to inhibit the conversion of testosterone to 5α-dihydrotestosterone (DHT), finasteride may cause abnormalities of the external genitalia of a male fetus of a pregnant female who receives finasteride. (फिनास्टेराइड लेबल, निषेध (कॉन्ट्राइंडिकेशन))

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (एस्ट्राडियोल और नॉरएथिस्टेरोन लेबल, चेतावनियां और सावधानियां)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (कंजुगेटेड एस्ट्रोजन लेबल, सावधानियां)

Free hormone concentrations, such as testosterone and estradiol, may be decreased. (कंजुगेटेड एस्ट्रोजन और बैज़ेडॉक्सीफेन लेबल, चेतावनियां और सावधानियां)

PRECAUTIONS General Induction of androgen secretion by hCG may cause fluid retention. (कोरियोगोनाडोट्रोपिन अल्फा लेबल, सावधानियां)

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval. (गोसेरेलिन लेबल, चेतावनियां और सावधानियां)

…medications, pramlintide acetate, insulin, angiotensin converting enzyme (ACE) inhibitors, H 2 receptor antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs… (ग्लिमेपिराइड लेबल, दवाओं के इंटरैक्शन)

Hypercalcemia in Patients with Metastatic Breast Cancer As with other additive hormonal therapy (estrogens and androgens), hypercalcemia has been reported in some breast cancer patients with bone metastases within a few weeks of starting treatment with tamoxifen. (टैमोक्सीफेन लेबल, चेतावनियां और सावधानियां)

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment. (ट्रिप्टोरेलिन लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

…anti-diabetic medications, pramlintide acetate, insulin, angiotensin converting enzyme (ACE) inhibitors, H2 receptor antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs… (पियोग्लिटाज़ोन और ग्लिमेपिराइड लेबल, दवाओं के इंटरैक्शन)

Some patients had serious bleeding including intracranial, retroperitoneal, and gastrointestinal requiring blood transfusion and/or administration of vitamin K. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

For Men : Clinical monitoring for spermatogenesis utilizes the following indirect or direct measures: Serum testosterone level Semen analysis 5.11 FOLLISTIM Pen The FOLLISTIM Pen is intended only for use with FOLLISTIM AQ Cartridge. (फॉलिट्रोपिन लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (फ्लुड्रोकॉर्टिसोन लेबल, दवाओं के इंटरैक्शन)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Clinical studies have shown that with co-administration of bicalutamide, mean midazolam (a CYP 3A4 substrate) levels may be increased 1.5-fold (for C max ) and 1.9-fold (for AUC). (बाइकैलुटामाइड लेबल, दवाओं के इंटरैक्शन)

The following laboratory tests may be affected by progestins including MPA Injectable Suspension, USP: (a) Plasma and urinary steroid levels are decreased (e.g., progesterone, estradiol, pregnanediol, testosterone, cortisol). (मेड्रोक्सीप्रोजेस्टेरोन लेबल, दवाओं के इंटरैक्शन)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Reproductive effects: Include decreased testosterone and increased prolactin levels. (रैमेल्टियॉन लेबल, चेतावनियां और सावधानियां)

Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nicotinic Acid These drugs may decrease serum TBG concentration. (लियोथायरोनिन लेबल, दवाओं के इंटरैक्शन)

Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (लेवोथायरोक्सिन लेबल, दवाओं के इंटरैक्शन)

Weak CYP3A4 Inhibitors Weak CYP3A4 inhibitors (such as alprazolam, amiodarone, amlodipine, atorvastatin, bicalutamide, cilostazol, cimetidine, cyclosporine, fluoxetine, fluvoxamine, ginkgo, goldenseal, isoniazid, lapatinib, nilotinib, pazopanib, ranitidine, ranolazine, ticagrelor, zileuton) can increase lomitapide exposure approximately 2-fold [see Clinical Pharmacology… (लोमिटापाइड लेबल, दवाओं के इंटरैक्शन)

However, clinical studies have shown that lovastatin does not reduce basal plasma cortisol concentration or impair adrenal reserve, and does not reduce basal plasma testosterone concentration. (लोवास्टेटिन लेबल, दवाओं के इंटरैक्शन)

Tumor Flare: Increased serum testosterone (~ 50% above baseline) may occur when initiating treatment with LUPRON DEPOT. (ल्यूप्रोलाइड लेबल, चेतावनियां और सावधानियां)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Some patients had serious bleeding including intracranial, retroperitoneal, and gastrointestinal requiring blood transfusion and/or administration of vitamin K. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (स्पिरोनोलैक्टोन और हाइड्रोक्लोरोथायज़ाइड लेबल, दवाओं के इंटरैक्शन)

Closely monitor the Prothrombin Time (PT) and International Normalized Ratio (INR), and adjust the anticoagulant dose as needed. (बाइकैलुटामाइड लेबल, चेतावनियां और सावधानियां)